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Generated: November 18, 2017

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Claims for Patent: 4,451,458

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Claims for Patent: 4,451,458

Title: Method for the treatment of post-operative thrombosis
Abstract:The invention provides novel pharmaceutical compositions useful in the treatment of thrombosis in mammals, comprising a mixture of dihydroergotamine or a related ergot alkaloid and heparin.
Inventor(s): Buhlmann; Hans (Nuremberg, DE), Welzel; Dieter (Nuremberg, DE)
Assignee: Sandoz Ltd. (Basel, CH)
Application Number:06/379,272
Patent Claims: 1. A method for the prophylactic treatment of post-operative thrombosis in mammals, comprising parenterally administering dihydroergotamine in conjunction with heparin, wherein the administration is effected with a unit dose comprising about 0.5 mg. of dihydroergotamine and about 2500-5000 I.U. of heparin and said doses are administered two to four times daily.

2. A pharmaceutical composition useful in the prophylactic treatment of post-operative thrombosis in mammals, comprising in unit dosage form about 0.5 mg. of dihydroergotamine and about 2500-5000 I.U. of heparin.

3. A pharmaceutical composition useful in the prophylactic treatment of post-operative thrombosis in mammals, comprising in unit dosage form about 0.5 mg. of dihydroergotamine and about 5000 I.U. of heparin.
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US Army
Dow

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