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Serving hundreds of leading biopharmaceutical companies globally:

Farmers Insurance
Chinese Patent Office
Queensland Health
Fish and Richardson
Boehringer Ingelheim

Generated: May 21, 2018

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Claims for Patent: 4,432,963

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Summary for Patent: 4,432,963
Title: Radiographic scanning agent
Abstract:A composition and method for the preparation of a technetium-99m-based scanning agent are disclosed. The scanning agent is prepared from .sup.99m Tc, in a +3, +4 and/or +5 oxidation state, and a methanehydroxydiphosphonate bone-seeking agent which carries the radionuclide to bone mineral. The methanehydroxydiphosphonate agent provides scan sharpness equivalent or superior to commercial scanning agents, and is superior for detecting myocardial infarcts, as compared with commercial scanning agents such as ethane-1-hydroxy-1,1-diphosphonate and methanediphosphonate.
Inventor(s): Bevan; John A. (Cincinnati, OH)
Assignee: Mallinckrodt, Inc. (St. Louis, MO)
Application Number:06/225,151
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 4,432,963
Patent Claims: 1. Water-soluble stannous methanehydroxydiphosphonate.

2. Water-soluble ferrous methanehydroxydiphosphonate.

3. Water-soluble chromous methanehydroxydiphosphonate.

4. Water-soluble titanous methanehydroxydiphosphonate.

5. The water-soluble composition of matter .sup.99m Tc-methanehydroxydiphosphonate.

6. The water-soluble composition of matter .sup.99m Tc-methanehydroxydiphosphonate-tin.

7. The water-soluble composition of matter .sup.99m Tc-methanehydroxydiphosphonate-iron.

8. The water-soluble composition of matter .sup.99m Tc-methanehydroxydiphosphonate-chromium.

9. The water-soluble composition of matter .sup.99m Tc-methanehydroxydiphosphonate-titanium.

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Serving hundreds of leading biopharmaceutical companies globally:

Harvard Business School
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