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Last Updated: April 25, 2024

Claims for Patent: 4,425,363

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Summary for Patent: 4,425,363

Title:	Treatment of tardive dyskinesia in mammals
Abstract:	A method of Treatment of Tardive Dyskinesia (TD) in humans by the administration of the compound of the formula ##STR1## or a pharmaceutically acceptable acid addition salt thereof in a non-toxic, effective therapeutic amount (calculated as base) to a human in need thereof.
Inventor(s):	Stern; Warren C. (Raleigh, NC)
Assignee:	Burroughs Wellcome Co. (Research Triangle Park, NC)
Application Number:	06/395,118
Patent Claims:	1. A method of treating Tardive Dyskinesia in a human having Tardive Dyskinesia which comprises administering to said human an effective non-toxic Tardive Dyskinesia amount of a compound of the formula (I) ##STR3## or a pharmaceutically acceptable and acid addition salt thereof. 2. The method of claim 1 in which a pharmaceutically acceptable salt thereof is administered. 3. The method of claim 2 in which the salt is the hydrochloride salt. 4. The method of claim 1, 2, or 3 in which the compound or salt is administered in a pharmaceutically acceptable carrier therefore. 5. The method of claim 4 in which the compound or salt is administered orally. 6. The method of claim 4 in which the compound or salt is administered parenterally. 7. A method of treating Tardive Dyskinesia in a human having Tardive Dyskinesia which comprises orally administering to said human an effective acid addition Tardive Dyskinesia treatment amount of a pharmaceutically acceptable acid addition salt of the compound of the formula (I) ##STR4## 8. The method of claim 7 in which the salt is the hydrochloric salt. 9. The method of claim 7 or 8 in which the salt is administered in a pharmaceutically acceptable carrier therefor in the form of a tablet or capsule. 10. A method of treating Tardive Dyskinesia in a human having Tardive Dyskinesia which comprises parenterally administering to said human an effective non-toxic Tardive Dyskinesia treatment amount of a parenteral composition containing a pharmaceutically acceptable acid addition salt of the compound of the formula (I) ##STR5##

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