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Last Updated: April 19, 2024

Claims for Patent: 4,404,216


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Summary for Patent: 4,404,216
Title: Antifungal 1,3-bis-triazolyl-2-propanol derivative
Abstract:2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol and its pharmaceutically acceptable acid addition salts are disclosed. This particular bis-triazole derivative and its aforesaid salts are useful for treating fungal infections in animals, including humans. Methods for preparing these compounds from known starting materials are provided.
Inventor(s): Richardson; Kenneth (Canterbury, GB2)
Assignee: Pfizer Inc. (New York, NY)
Application Number:06/383,866
Patent Claims: 1. An antifungal compound selected from the group consisting of 2-(2,4-difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol and the pharmaceutically acceptable acid addition salts thereof.

2. A pharmaceutical composition comprising a pharmaceutically acceptable carrier and an effective antifungal amount of a compound as claimed in claim 1.

3. A method for treating fungal infections in a warm-blooded animal, which comprises administering to said animal an effective antifungal amount of a compound as claimed in claim 1.

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