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Claims for Patent: 4,396,598

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Claims for Patent: 4,396,598

Title: Triiodoisophthalamide X-ray contrast agent
Abstract:Novel X-ray contrast agents, i.e., N,N'-bis(2,3-dihydroxypropyl)-5-N-(2-hydroxyethyl)glycolamido-2,4,6-triiod oisophthalamide.
Inventor(s): Lin; Youlin (Chesterfield, MO)
Assignee: Mallinckrodt, Inc. (St. Louis, MO)
Application Number:06/338,382
Patent Claims: 1. N,N'-Bis(2,3- dihydroxypropyl)-5-N-(2-hydroxyethyl)glycolamido-2,4,6-triiodoisophthalamid e.

2. A radiological composition containing N,N'-bis(2,3-dihydroxypropyl)-5-N-(2-hydroxyethyl)glycolamido-2,4,6-triiod oisophthalamide in a sufficient amount to provide satisfactory X-ray visualization together with a pharmaceutically acceptable radiological vehicle.

3. In a method for X-ray visualization wherein a radiological composition containing an X-ray contrast agent in a pharmaceutically acceptable radiological vehicle is injected in a sufficient amount to provide adequate visualization and thereafter X-ray visualization carried out, the improvement comprising or utilizing as the radiological composition a composition containing N,N'-bis(2,3-dihydroxypropyl)-5-N-(2-hydroxyethyl)glycolamido-2,4,6-triiod oisophthalamide in a sufficient amount to provide satisfactory X-ray visualization together with a pharmaceutically acceptable radiological vehicle.
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