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Claims for Patent: 4,387,089

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Claims for Patent: 4,387,089

Title: 4-(1,1-Dimethylethyl)-4'-methoxydibenzoylmethane
Abstract:The novel 4-(1,1-Dimethylethyl)-4'-methoxydibenzoylmethane is useful as a sunscreen agent. It exhibits outstanding UV-A absorbing qualities in that it brings about a considerable retardation in the ageing of the skin with excellent skin tolerance and stability (light, heat and moisture). 4-(1,1-Dimethylethyl)-4'-methoxydibenzoylmethane furthermore improves the protective action of UV B-filters, i.e. of substances which absorb the erythema-producing UV B-radiation in the range of about 290 to 320 mm.
Inventor(s): De Polo; Karl-Fred (Onex, CH)
Assignee: Givaudan Corporation (Clifton, NJ)
Application Number:06/264,774
Patent Claims: 1. 4-(1,1-Dimethylethyl)-4'-methoxydibenzoylmethane.

2. A light-screen composition comprising an effective ultra violet absorbing amount of 4-(1,1-dimethylethyl)-4'-methoxydibenzoylmethane and at least one other organic material.

3. A light-screen composition according to claim 2 which contains 4-(1,1-dimethylethyl)-4'-methoxydibenzoylmethane in combination with UV B-filter.

4. A light-screen composition according to claim 2 or claim 3, wherein about 1 wt. % to 6 wt. % of 4-(1,1-dimethylethyl)-4'-methoxydibenzoylmethane is present.

5. A sun-screen composition comprising 2 wt. % to 5 wt. % of 4-(1,1-dimethylethyl)-4'-methoxydibenzoylmethane and 2.0 wt. % to 10.0 wt. % of 2-ethylhexyl p-methoxycinnamate.

6. A method for preparing a light screening composition which comprises incorporating 4-(1,1-dimethylethyl-4'-methoxydibenzoylmethane into a cosmetic base.

7. The method of claim 6 wherein the amount of 4-(1,1-dimethylethyl-4'-methoxydibenzoylmethane incorporated is between 1% and 6% by weight of the total composition.

8. The method of claim 6 wherein there is also incorporated a UV B-filter.

9. The method of claim 7 wherein there is also incorporated 1% to 12% by weight of 2-ethylhexyl-p-methoxycinnamate.

10. A topical preparation for application on the skin which comprises an effective amount of 4(1,1-dimethyl)-4'-methoxydibenzoylmethane as a UV-A absorber in a suitable carrier.

11. The preparation of claim 10 wherein the carrier is a suitable cosmetic base.

12. The preparation of claims 10 or 11 wherein the 4-(1,1-dimethylethyl)-4'-methoxydibenzoylmethane is present at a level of 1% by weight to 6% by weight.

13. The preparation of claims 10 or 11 wherein the 4-(1,1-dimethylethyl)-4'-methoxydibenzoylmethane is present at a level of 2% by weight to 5% by weight and wherein there is also present 2-ethylhexyl p-methoxycinnamate at a level of 2% by weight to 10% by weight.

14. A method for protecting the skin from the effects of U.V.-A radiation which comprises applying to the skin an effective amount of 4-(1,1-dimethylethyl)-4'-methoxydibenzoylmethane in a carrier suitable for application on the skin.

15. A method according to claim 14 wherein the carrier is a cosmetic base.

16. The method of claims 14 or 15 wherein the 4-(1,1-dimethylethyl)-4'-methoxydibenzoylmethane is applied as part of a formulation wherein it is present at a concentration of 1% by weight to 6% by weight of the formulation.

17. The method of claims 14 or 15 wherein the 4-(1,1-dimethylethyl)-4'-methoxydibenzoylmethane is applied as part of a formulation wherein it is present at a concentration of 2% by weight to 5% by weight and wherein there is also present 2-ethylhexyl p-methoxycinnamate at a level of 2% by weight to 10% by weight.
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