Flexible Flat-Rate Plans

Flat-rate pricing for predictable budgeting

Short-term plans for project- or client-based billing

► Plans and Pricing

Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

DrugPatentWatch Database Preview

Claims for Patent: 4,324,779

« Back to Dashboard

Claims for Patent: 4,324,779

Title: Method for treating hypertonia with N-(2-furfuryl)-4-chloro-5-sulfamoyl-anthranilic acid and preparations thereof
Abstract:A method for treating hypertonia with a preparation of N-(2-furfuryl)-4-chloro-5-sulfamoyl-anthranilic acid having a slightly retarded release, wherein the release of the active substance in vitro, measured in the flow through-cell to Dibbern, is not more than 5% after 1 hour in a buffer solution of pH 1.5 and about 10 to at most 25% of the active substance content after a two-hour treatment in a buffer solution of pH 5.5.
Inventor(s): Dahlhausen; Gebhard (Kronberg, DE), Dibbern; Hans-Werner (Kelkheim, DE), Fulberth (Kelkheim, DE), Ross; Gerhard (Kriftel, DE)
Assignee: Hoechst Aktiengesellschaft (Frankfurt am Main, DE)
Application Number:06/077,181
Patent Claims: 1. A furosemide-containing pellet for the oral administration of furosemide, said pellet consisting essentially of a core of furosemide having thereover a sustained-release coating which starts to dissolve in a weakly acid medium, which coating, when its release characteristics are measured in vitro in a flow-through-cell according to Dibbern,

(a) releases not more than 5 percent of said furosemide into a buffer solution having a pH of 1.5 during the first hour of measurement in said cell;

(b) releases about 10 to at most 25 percent of said furosemide into a buffer solution having a pH of 5.5 during the second hour of measurement in said cell; and

(c) releases the remainder of said furosemide substantially completely into a buffer solution having a pH of 7.5 during the third and fourth hours of measurement in said cell.
« Back to Dashboard

For more information try a trial or see the database preview and plans and pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.