Claims for Patent: 4,260,769
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Summary for Patent: 4,260,769
| Title: | 5,5-Diphenylhydantoins |
| Abstract: | Novel 5,5-diphenylhydantoins useful as anticonvulsants, antiepileptics and antiarrhythmics have the structural formula: |
| Inventor(s): | Valentino J. Stella, Kenneth B. Sloan |
| Assignee: | Bristol Myers Squibb Pharma Co , Merck and Co Inc |
| Application Number: | US06/033,234 |
| Patent Claims: |
1. A 5,5-diphenylhydantoin compound having the structural formula: ##STR12## wherein each R is independently selected from the group consisting of hydrogen and --CH(R1)--O--P(O)(OH)2, wherein R1 is selected from the group consisting of hydrogen and C1 -C7 straight or branched chain alkyl; with the proviso that the R's cannot simultaneously be hydrogen; or the pharmaceutically acceptable acid addition or basic salts, C1 -C4 alkylhalide quaternary salts or N-oxide thereof. 2. The compound as defined by claim 1, wherein either R is hydrogen, with the other being --CH(R1)--O--P(O)(OH)2. 3. The compound as defined by claim 1, same being 3-phosphoryloxymethyl-5,5-diphenylhydantoin. |
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