Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing
|Abstract:||Novel 5,5-diphenylhydantoins useful as anticonvulsants, antiepileptics and antiarrhythmics have the structural formula: ##STR1## wherein each R is hydrogen or --CH(R.sub.1)--X--P(O)(OH).sub.2, R.sub.1 is hydrogen or C.sub.1 -C.sub.7 straight or branched chain alkyl, and X is O or S, with the proviso that both R's cannot simultaneously be hydrogen.|
|Inventor(s):||Stella; Valentino J. (Lawrence, KS), Sloan; Kenneth B. (Eudora, KS)|
|Assignee:||INTERx Research Corporation (Lawrence, KS)|
1. A 5,5-diphenylhydantoin compound having the structural formula: ##STR12## wherein each R is independently selected from the group consisting of hydrogen and
--CH(R.sub.1)--O--P(O)(OH).sub.2, wherein R.sub.1 is selected from the group consisting of hydrogen and C.sub.1 -C.sub.7 straight or branched chain alkyl; with the proviso that the R's cannot simultaneously be hydrogen; or the pharmaceutically
acceptable acid addition or basic salts, C.sub.1 -C.sub.4 alkylhalide quaternary salts or N-oxide thereof.
2. The compound as defined by claim 1, wherein either R is hydrogen, with the other being --CH(R.sub.1)--O--P(O)(OH).sub.2.
3. The compound as defined by claim 1, same being 3-phosphoryloxymethyl-5,5-diphenylhydantoin.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.