Generated: April 23, 2017
|Abstract:||A tablet suitable for use in the treatment of microbial infections, which tablet comprises from 80 to 98% (w/w) of a combination of a 2,4-diaminopyrimidine with a sulphonamide and not more than 20% (w/w) of both a granulating and a disintegrating agent, the combination having a particle size less than 40 .mu.m and the disintegrating agent having a swelling capacity greater than 5 ml/g.|
|Inventor(s):||Torode; Allan J. (Basildon, GB2), Harden; David (Sidcup, GB2), Spence; John (Bickley, GB2)|
|Assignee:||Burroughs Wellcome Co. (Research Triangle Park, NC)|
1. A tablet which comprises from 90 to 98% (w/w) of a combination of trimethoprim with sulphamethoxazole, the combination having a particle size from 1 to 40 .mu.m, from 1 to
5% (w/w) of a granulating agent, and from 1 to 5% (w/w) of a disintegrating agent having a swelling capacity from 5 to about 25 ml/g, the tablet having a hardness of about 9.8 to 20 kg and a disintegration time of less than 9 minutes.
2. A tablet according to claim 1, wherein the tablet has a hardness of about 9.8 to about 14.8 kg.
3. A tablet according to claim 1 wherein the disintegration time is from 45 seconds to about 5 minutes.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.