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Last Updated: March 26, 2026

Claims for Patent: 4,188,390

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Summary for Patent: 4,188,390

Title:	Antihypertensive 4-amino-2-[4-(1,4-benzodioxan-2-carbonyl) piperazin-1-yl or homopiperazin-1-yl]quinazolines
Abstract:	Compounds having the formula and pharmaceutically acceptable salts thereof wherein R represents 6,7-di(lower alkoxy) or 6,7,8-tri(lower alkoxy); m is 1 or 2, X is -CHR1- or -CH2CH2-; each R1 and R0 may be the same or different and is hydrogen or lower alkyl; each of R2 and R3 is hydrogen, lower alkoxy, lower alkyl, halogen, lower alkanoyl, lower alkoxycarbonyl, -CONR4R5 or -SO2NR4R5 wherein each of R4 and R5 is hydrogen or lower alkyl; processes for their preparation; and their use as regulators of the cardiovascular system, and particularly in the treatment of hypertension.
Inventor(s):	Simon F. Campbell
Assignee:	Pfizer Corp SRL
Application Number:	US05/952,317
Patent Claims:

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