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Claims for Patent: 4,182,763

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Claims for Patent: 4,182,763

Title: Buspirone anti-anxiety method
Abstract:Buspirone hydrochloride is an effective anti-anxiety agent for the palliative treatment of neurotic patients in which symptoms of anxiety are predominant at doses which are without observable effect in either normal individuals or psychotic patients.
Inventor(s): Casten; George P. (Evansville, IN), McKinney; Gordon R. (Evansville, IN), Newton; Roger E. (Evansville, IN), Tompkins; E. Crosby (Evansville, IN), Weikel, Jr.; John H. (Mt. Vernon, IN)
Assignee: Mead Johnson & Company (Evansville, IN)
Application Number:05/908,597
Patent Claims: 1. A method for the palliative treatment of neurosis in which anxiety symptoms are prominent which comprises administering a non-toxic anxiolytically effective dose of buspirone or a pharmaceutically acceptable acid addition salt thereof to a neurotic patient.

2. The method of claim 1 wherein buspirone hydrochloride is employed, and dosage is by the oral route.

3. The method of claim 2 wherein said patient is suffering from anxiety neurosis.

4. The method of claim 2 wherein said patient is suffering from anxiety neurosis with depressive symptoms.

5. The method of claims 2, 3, or 5 wherein said patient is an adult and a daily dose of from 10 mg. to 60 mg. is employed.

6. The method of claim 5 wherein said daily dose is divided and administered b.i.d.

7. The method of claim 5 wherein said daily dose is divided and administered t.i.d.

8. The method of claim 2 wherein the maximum total daily dose of up to about 100 mg.

9. The method of claims 2, 3, or 4 wherein said patient is an adult and a daily dose of from 20 mg. to 30 mg. is employed.
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