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Summary for Patent: 4,182,763
|Title:||Buspirone anti-anxiety method|
|Abstract:||Buspirone hydrochloride is an effective anti-anxiety agent for the palliative treatment of neurotic patients in which symptoms of anxiety are predominant at doses which are without observable effect in either normal individuals or psychotic patients.|
|Inventor(s):||Casten; George P. (Evansville, IN), McKinney; Gordon R. (Evansville, IN), Newton; Roger E. (Evansville, IN), Tompkins; E. Crosby (Evansville, IN), Weikel, Jr.; John H. (Mt. Vernon, IN)|
|Assignee:||Mead Johnson & Company (Evansville, IN)|
1. A method for the palliative treatment of neurosis in which anxiety symptoms are prominent which comprises administering a non-toxic anxiolytically effective dose of
buspirone or a pharmaceutically acceptable acid addition salt thereof to a neurotic patient.
2. The method of claim 1 wherein buspirone hydrochloride is employed, and dosage is by the oral route.
3. The method of claim 2 wherein said patient is suffering from anxiety neurosis.
4. The method of claim 2 wherein said patient is suffering from anxiety neurosis with depressive symptoms.
5. The method of claims 2, 3, or 5 wherein said patient is an adult and a daily dose of from 10 mg. to 60 mg. is employed.
6. The method of claim 5 wherein said daily dose is divided and administered b.i.d.
7. The method of claim 5 wherein said daily dose is divided and administered t.i.d.
8. The method of claim 2 wherein the maximum total daily dose of up to about 100 mg.
9. The method of claims 2, 3, or 4 wherein said patient is an adult and a daily dose of from 20 mg. to 30 mg. is employed.
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