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|Abstract:||Process for production of 3,4-dihydro-2-methyl-4-oxo-2H-1,2-benzothiazine-3-carboxylic acid-1,1-dioxide by hydrolysis, in the presence of hydroxide ions, of an alkyl or aralkyl ester thereof followed by precipitation of the acid at pH below 6.0 and its use as an intermediate for the production of N-(2-pyridyl)-3,4-dihydro-2-methyl-4-oxo-2H-1,2-benzothiazine-3-carboxamid e-1,1-dioxide and the analogous N-(2-thiazolyl)-compound, effective antiinflammatory agents.|
|Inventor(s):||Hammen; Philip D. (East Lyme, CT)|
|Assignee:||Pfizer Inc. (New York, NY)|
|Patent Claims:||1. Crystalline 3,4-dihydro-2-methyl-4-oxo-2H-1,2-benzothiazine-3-carboxylic acid-1,1-dioxide.|
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