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Claims for Patent: 4,087,544

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Claims for Patent: 4,087,544

Title: Treatment of cranial dysfunctions using novel cyclic amino acids
Abstract:The present invention is concerned with new cyclic amino acids and with the preparation thereof.
Inventor(s): Satzinger; Gerhard (Denzlingen, DT), Hartenstein; Johannes (Wittental, DT), Herrmann; Manfred (St. Peter, DT), Heldt; Wolfgang (Wasser, DT)
Assignee: Warner-Lambert Company (Morris Plains, NJ)
Application Number:05/791,677
Patent Claims: 1. A method of treating certain forms of epilepsy, faintness attacks, hypokinesia and cranial traumas which comprises the enteral or parenteral administration to a mammal having such cranial dysfunction of an amount effective for such treatment of at least one compound or its pharmaceutically acceptable salt of the formula: ##STR6## wherein R is hydrogen or a lower alkyl and n is 4, 5, or 6.

2. The method of claim 1 wherein the compound is 1-Aminomethyl-1-cyclohexane-acetic acid.

3. The method of claim 1 wherein the compound is Ethyl 1-aminomethyl-1-cyclohexane-acetate.

4. The method of claim 1 wherein the compound is 1-Aminomethyl-1-cycloheptane-acetic acid.

5. The method of claim 1 wherein the compound is 1-Aminomethyl-1-cyclopentane-acetic acid.

6. The method of claim 1 wherein the compound is Methyl 1-aminomethyl-1-cyclohexane-acetate.

7. The method of claim 1 wherein the compound is n-Butyl 1-aminomethyl-1-cyclohexane-acetate.

8. The method of claim 1 wherein the compound is Methyl 1-aminomethyl-1-cycloheptane-acetate.

9. The method of claim 1 wherein the compound is n-Butyl 1-aminomethyl-1-cycloheptane-acetate . toluene sulfonate.

10. The method of claim 1 wherein the compound is 1-Aminomethyl-1-cyclopentane-acetate . benzene-sulfonate.

11. The method of claim 1 wherein the compound is n-Butyl 1-aminomethyl-1-cyclopentane-acetate.
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