Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

Serving leading biopharmaceutical companies globally:

US Army
Harvard Business School
Fish and Richardson
US Department of Justice

Generated: February 21, 2018

DrugPatentWatch Database Preview

Claims for Patent: 4,060,691

« Back to Dashboard

Summary for Patent: 4,060,691
Title: 7-{3-Hydroxy-2-[4-hydroxy-4-(lower alkyl)-trans-1-octen-1-yl]-5-oxocyclopent-1-yl}heptanoic acids and esters
Abstract:7-{3-Hydroxy-2-[4-hydroxy-4-(lower alkyl)-trans-1-octen-1-yl]-5-oxocyclopent-1-yl{heptanoic acids and esters, displaying valuable pharmacological properties, e.g., gastric anti-secretory, are produced by the reaction of a 7-(3-oxygenated-5-oxocyclopent-1-en-1-yl)heptanoic acid or ester with the appropriate organometallic reagent.
Inventor(s): Collins; Paul W. (Deerfield, IL), Pappo; Raphael (Skokie, IL)
Assignee: G. D. Searle & Co. (Chicago, IL)
Application Number:05/642,830
Patent Claims: 1. A compound of the formula

wherein R.sub.1 is hydrogen or lower alkyl; R.sub.2 and R.sub.3 are hydrogen or a lower alkanoyl, tetrahydropyran-2-yl, or tri(lower

2. The compound according to claim 1 of the formula ##STR23## wherein R.sub.1 is hydrogen or lower alkyl; and R.sub.4 is a lower alkyl radical.

3. The compound according to claim 1 which is methyl 7-[(3(R)-hydroxy-2.beta.-(4(S)-4-hydroxy-4-methyl-trans-1-octen-1-yl)-5-ox ocyclopent-1.alpha.-yl]heptanoate.

4. The compound which is racemic methyl 7-[(3(R)-hydroxy-2.beta.-(4(S)-4-hydroxy-4-methyl-trans-1-octen-1-yl)-5-ox ocyclopent-1.alpha.-yl]heptanoate.

5. The compound which is methyl 7-[(3(R)-hydroxy-2.beta.-(4(RS)-4-hydroxy-4-methyl-trans-1-octen-1-yl)-5-o xocyclopent-1.alpha.-yl]heptanoate.

For more information try a trial or see the plans and pricing

Serving hundreds of leading biopharmaceutical companies globally:

Chinese Patent Office
Boehringer Ingelheim
Express Scripts

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.