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Generated: September 21, 2017

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Title: Antihypertensive agents
Abstract:Described are antihypertensive agents selected from the class consisting of 2[4(tetrahydro-2-furoyl)-piperazino]-4-amino-6,7-dimethoxyquinazoline and 2-[4(tetrahydropyran-2-carbonyl)-piperazinyl]-4-amino-6,7-dimethoxyquinazo line, and pharmaceutically acceptable acid addition salts thereof. The compounds are highly water soluble and can be administered in time release form as well as parenterally, including intravenously.
Inventor(s): Winn; Martin (Deerfield, IL), Kyncl; Jaroslav (Lake Bluff, IL), Dunnigan; Daniel Ambrose (Winthrop Harbor, IL), Jones; Peter Hadley (Lake Forest, IL)
Assignee: Abbott Laboratories (North Chicago, IL)
Application Number:05/621,980
Patent Claims: 1. A compound selected from the group consisting of 2-[4(tetrahydro-2-furoyl)-piperazino]-4-amino-6,7-dimethoxyquinazoline and 2-[4(tetrahydropyran-2-carbonyl)piperazinyl]-4-amino-6,7-dimethoxyquinazol ine and pharmaceutically acceptable acid addition salts thereof.

2. A compound in accordance with Claim 1: 2-[4(tetrahydro-2-furoyl)-piperazino]-4-amino-6,7-dimethoxyquinazoline hydrochloride.

3. A compound in accordance with Claim 1: 2-[4(tetrahydropyran-2-carbonyl)piperazinyl]-4-amino-6,7-dimethoxyquinazol ine hydrochloride.
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Cerilliant
McKesson
US Department of Justice
US Army
Fuji
Deloitte
Healthtrust
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Federal Trade Commission
Chinese Patent Office

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