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Last Updated: April 18, 2024

Claims for Patent: 4,018,895


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Summary for Patent: 4,018,895
Title: Aryloxyphenylpropylamines in treating depression
Abstract:3-Aryloxy-3-phenylpropylamines and acid additions salts thereof, useful as psychotropic agents, particularly as anti-depressants.
Inventor(s): Molloy; Bryan B. (Indianapolis, IN), Schmiegel; Klaus K. (Indianapolis, IN)
Assignee: Eli Lilly and Company (Indianapolis, IN)
Application Number:05/614,094
Patent Claims: 1. A method of treating human suffering from depression which comprises administering to said human an effective antidepressant dose of a compound of the formula: ##STR7## wherein each R' is independently hydrogen or methyl; wherein R is naphthyl or ##STR8## wherein R" and R'" are halo, trifluoromethyl, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.3 alkyloxy or C.sub.3 -C.sub.4 alkenyl; and

wherein n and m are 0, 1 or 2; and acid addition salts thereof formed with a pharmaceutically-acceptable acid.

2. A method according to claim 1, in which from 1 to 200 mg./day of the compound is administered.

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