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Serving leading biopharmaceutical companies globally:

Cantor Fitzgerald
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Generated: November 24, 2017

DrugPatentWatch Database Preview

Claims for Patent: 4,011,258

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Claims for Patent: 4,011,258

Title: Orally active bronchospasmolytic compounds
Abstract:Novel compounds are disclosed having useful activity as bronchodilators of improved longevity of action and reduced incidence of side effects. These compounds are described by the formula: ##STR1## wherein R.sub.1 is a member of the class consisting of tertiary butyl and cyclobutyl, and R.sub.2 is a hydrogen or 2 to 5 carbon atom acyl radical, and pharmaceutically acceptable salts thereof. The activity of these compounds is compared to previously known bronchodilators such as 1-(3', 5'-dihydroxyphenyl)-2-(isopropylamino)-ethanol, having the common name orciprenaline, and 1-(3', 4'-dihydroxyphenyl-2-isopropylamino-ethanol, having the common name isoprenaline.
Inventor(s): Wetterlin; Kjell Ingvar Leopold (Sandby, SW), Svensson; Leif Ake (Lund, SW)
Assignee: Aktiebolaget Draco (Lund, SW)
Application Number:05/593,424
Patent Claims: 1. A compound effective for producing bronchial dilation in animals, including humans, selected from the group consisting of

i. ethanol amines having the formulas ##STR22## wherein R.sub.2 is the acyl radical of a 2-5 carbon fatty acid and ii. pharmaceutically acceptable salts thereof.

2. The compound according to claim 1 having the formula ##STR23## and pharmaceutically acceptable salts thereof.

3. The compound according to claim 1 having the formula ##STR24##
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Serving leading biopharmaceutical companies globally:

Express Scripts
Cantor Fitzgerald
US Army

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