|Title:||Orally active bronchospasmolytic compounds|
|Abstract:||Novel compounds are disclosed having useful activity as bronchodilators of improved longevity of action and reduced incidence of side effects. These compounds are described by the formula: ##STR1## wherein R.sub.1 is a member of the class consisting of tertiary butyl and cyclobutyl, and R.sub.2 is a hydrogen or 2 to 5 carbon atom acyl radical, and pharmaceutically acceptable salts thereof. The activity of these compounds is compared to previously known bronchodilators such as 1-(3', 5'-dihydroxyphenyl)-2-(isopropylamino)-ethanol, having the common name orciprenaline, and 1-(3', 4'-dihydroxyphenyl-2-isopropylamino-ethanol, having the common name isoprenaline.|
|Inventor(s):||Wetterlin; Kjell Ingvar Leopold (Sandby, SW), Svensson; Leif Ake (Lund, SW)|
|Assignee:||Aktiebolaget Draco (Lund, SW)|
1. A compound effective for producing bronchial dilation in animals, including humans, selected from the group consisting of
i. ethanol amines having the formulas ##STR22## wherein R.sub.2 is the acyl radical of a 2-5 carbon fatty acid and ii. pharmaceutically acceptable salts thereof.
2. The compound according to claim 1 having the formula ##STR23## and pharmaceutically acceptable salts thereof.
3. The compound according to claim 1 having the formula ##STR24##
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.