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Generated: May 27, 2018

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Claims for Patent: 4,009,197

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Summary for Patent: 4,009,197
Title: 2-(6-Substituted-2'-naphthyl) acetic acid derivatives and the salts and esters thereof
Abstract:2-(6'-Substituted-2'-naphthyl)acetic acid derivatives substituted at the 2-position of the acetic acid moiety with methyl, methylene or halomethylene and the salts and esters thereof have anti-inflammatory, analgesic and anti-pyretic activities.
Inventor(s): Fried; John H. (Palo Alto, CA), Harrison; Ian T. (Palo Alto, CA)
Assignee: Syntex Corporation (Panama, PM)
Application Number:05/573,483
Patent Claims: 1. The isoamyl ester of d 2-(6'-methoxy-2'-naphthyl)propionic acid.

2. A compound selected from the group consisting of 2-(6'-methoxy-2'-naphthyl)propionic acid and the pharmaceutically acceptable salts thereof.

3. A compound selected from the group consisting of d 2-(6'-methoxy-2'-naphthyl)propionic acid and the pharmaceutically acceptable salts thereof.

4. A compound selected from the group consisting of 2-(6'-difluoromethoxy-2'-naphthyl)propionic acid and the pharmaceutically acceptable salts thereof.

5. A compound of claim 4 selected from the group consisting of dl-, d- and 1-2-(6'-difluoromethoxy-2'-naphthyl)propionic acid.

6. As a compound of claim 5, d 2-(6'-difluoromethoxy-2'-naphthyl)propionic acid.

7. The sodium salt of d 2-(6'-methoxy-2'-naphthyl)propionic acid.

8. The sodium salt of 2-(6'-methoxy-2'-naphthyl)propionic acid.

9. The pharmaceutically acceptable salts of 2-(6'-methoxy-2'-naphthyl)propionic acid.

10. The pharmaceutically acceptable salts of d 2-(6'-methoxy-2'-naphthyl)propionic acid.

11. 1 isoamyl 2-(6'-methoxy-2'-naphthyl)propionate.

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Serving hundreds of leading biopharmaceutical companies globally:

Fish and Richardson
Cantor Fitzgerald
Teva
Medtronic
AstraZeneca
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Queensland Health
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