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Claims for Patent: 4,005,063

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Claims for Patent: 4,005,063

Title: [Des-gly].sup.10 -GnRH nonapeptide anide analogs in position 6 having ovulation-inducing activity
Abstract:An unnatural nonapeptide with improved biological activities surpassing those of the natural follicle-stimulating lutenizing hormone-releasing hormone (Gn--RH) is described. The new peptide induces ovulation in warm-blooded animals at an oral dose of 5-100 .mu.g./kg.
Inventor(s): Gendrich; Ronald Lee (Waukegan, IL), Rippel; Riemond Henry (Gurnee, IL), Seely; John Hunter (Lake Bluff, IL)
Assignee: Abbott Laboratories (North Chicago, IL)
Application Number:05/577,815
Patent Claims: 1. A nonapeptide of the formula:

wherein all aminoacids are present in their optical L-configuration and wherein X represents leucyl in the D-configuration.
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