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Summary for Patent: 4,005,063
|Title:||[Des-gly].sup.10 -GnRH nonapeptide anide analogs in position 6 having ovulation-inducing activity|
|Abstract:||An unnatural nonapeptide with improved biological activities surpassing those of the natural follicle-stimulating lutenizing hormone-releasing hormone (Gn--RH) is described. The new peptide induces ovulation in warm-blooded animals at an oral dose of 5-100 .mu.g./kg.|
|Inventor(s):||Gendrich; Ronald Lee (Waukegan, IL), Rippel; Riemond Henry (Gurnee, IL), Seely; John Hunter (Lake Bluff, IL)|
|Assignee:||Abbott Laboratories (North Chicago, IL)|
1. A nonapeptide of the formula:
wherein all aminoacids are present in their optical L-configuration and wherein X represents leucyl in the D-configuration.
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