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Serving 500+ biopharmaceutical companies globally:

Cantor Fitzgerald
US Army
Medtronic
Mallinckrodt
Healthtrust
Covington
Novartis
Deloitte
Queensland Health
Moodys

Generated: August 18, 2017

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Title: 1-Polyfluoroalkyl-1,4-benzodiazepin-2-thiones for effecting tranquilization, sedation and treating colvulsions
Abstract:Disclosed herein are 1-polyfluoroalkyl-1,4-benzodiazepin-2-thiones, a new class of chemical compounds particularly useful as sedatives, anti-anxiety agents and anti-convulsants.
Inventor(s): Steinman; Martin (Livingston, NJ)
Assignee: Schering Corporation (Kenilworth, NJ)
Application Number:05/494,002
Patent Claims: 1. A method for effecting tranquilization comprising administering to a mammal exhibiting symptoms of anxiety 7-chloro-1-(2,2,2-trifluoroethyl)-1,3-dihydro-5-(2-fluorophenyl)-2H-1,4-be nzodiazepin-2-thione or a pharmaceutically acceptable salt thereof in an amount sufficient to effect tranquilization.

2. A method for effecting sedation comprising administering to a mammal 7-chloro-1-(2,2,2-trifluoroethyl)-1,3-dihydro-5-(2-fluorophenyl)-2H-1,4-be nzodiazepin-2-thione or a pharmaceutically acceptable salt thereof in an amount sufficient to effect sedation.

3. A method for inhibiting convulsions comprising administering to a convulsion-prone mammal 7-chloro-1-(2,2,2-trifluoroethyl)-1,3-dihydro-5-(2-fluorophenyl)-2H-1,4-be nzodiazepin-2-thione or a pharmaceutically acceptable salt thereof in an amount sufficient to inhibit convulsions.
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Serving 500+ biopharmaceutical companies globally:

Chinese Patent Office
McKesson
Federal Trade Commission
US Department of Justice
Johnson and Johnson
Healthtrust
Fuji
Cipla
Fish and Richardson
Teva

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