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Serving leading biopharmaceutical companies globally:

Fish and Richardson
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Queensland Health
Argus Health
Chinese Patent Office

Generated: November 17, 2017

DrugPatentWatch Database Preview

Claims for Patent: 3,920,809

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Claims for Patent: 3,920,809

Title: Dibenzo(b,d)pyranone dispersions
Abstract:1-Hydroxy-3-alkyl-9-keto or 9-hydroxyhexahydro dibenzo[b,d]pyrans, useful as tranquilizers or hypotensive agents are dispersed with PVP or polyethylene glycol.
Inventor(s): Thakkar; Arvind L. (Indianapolis, IN)
Assignee: Eli Lilly and Company (Indianapolis, IN)
Application Number:05/413,012
Patent Claims: 1. A dispersion of 2-20 parts of polyvinylpyrrolidone having a molecular weight in the range 10,000-360,000 with one part of a compound of the formula ##SPC2##

wherein Z is ##EQU4## or ##EQU5## wherein each R is individually hydrogen or C.sub.1 -C.sub.3 alkanoyl, wherein R.sup.3 is hydrogen or methyl, wherein each R.sup.2 is either hydrogen or methyl, and both R.sup.2 groups are the same, and wherein R.sup.1 is C.sub.1 -C.sub.6 alkyl.

2. A dispersion according to claim 1 containing 1 part of 1-hydroxy-3-(1',1'-dimethylheptyl)-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro- 9H-dibenzo[b,d]pyran-9-one and 9 part of a polyvinylpyrrolidone having a molecular weight in the range 10,000-360,000.

3. A dispersion according to claim 1 wherein the compound is 1-hydroxy-3-(1',1'-dimethylheptyl)-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro- 9H-dibenzo[b,d]pyran-9-one.

4. A dispersion according to claim 3 of polyvinylpyrrolidone of molecular weight 40,000 and 1-hydroxy-3-(1',1'-dimethylheptyl)-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro- 9H-dibenzo[b,d]pyran-9-one.
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Cantor Fitzgerald
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US Department of Justice
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US Army

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