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Serving hundreds of leading biopharmaceutical companies globally:

Queensland Health
Dow
Covington
Boehringer Ingelheim
UBS
Accenture
Mallinckrodt
McKinsey
Farmers Insurance

Generated: May 27, 2018

DrugPatentWatch Database Preview

Claims for Patent: 3,910,924

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Summary for Patent: 3,910,924
Title: 3,4-Dihydrocarbostyril derivatives and a process for preparing the same
Abstract:A novel compound represented by the formula ##SPC1## Wherein R is defined as hereinafter, having a blocking activity on .beta.-adrenergic nerves, a novel intermediate useful for synthesis thereof and processes for preparing the same are disclosed.
Inventor(s): Tamura; Yasumitsu (Takarazuka, JA), Nakagawa; Kazuyuki (Tokushima, JA), Yoshizaki; Shiro (Komatsujima, JA), Murakami; Nanami (Tokushima, JA)
Assignee: Otsuka Pharmaceutical (Tokyo, JA)
Application Number:05/324,905
Patent Claims: 1. A 3,4-Dihydrocarbostyril derivative represented by the formula ##SPC6##

and the pharmaceutically acceptable acid addition salts thereof, wherein R represents a straight or branched alkyl group having 1 to 4 carbon atoms.

2. 5-(2-Hydroxy-3-methylamino)propoxy-3,4-dihydrocarbostryil according to claim 1.

3. 5-(2-Hydroxy-3-ethylamino)propoxy-3,4-dihydrocarbostyril according to claim 1.

4. 5-(2-Hydroxy-3-propylamino)propoxy-3,4-dihydrocarbostyril according to claim 1.

5. 5-(2-Hydroxy-3-butylamino)propoxy-3,4-dihydrocarbostyril according to claim 1.

6. 5-(2-Hydroxy-3-tert-butylamino)propoxy-3,4-dihydrocarbostyril according to claim 5.

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Serving hundreds of leading biopharmaceutical companies globally:

Queensland Health
Colorcon
Cerilliant
US Department of Justice
Medtronic
AstraZeneca
Daiichi Sankyo
UBS
US Army

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