Generated: April 27, 2017
|Title:||3,4-Dihydrocarbostyril derivatives and a process for preparing the same|
|Abstract:||A novel compound represented by the formula ##SPC1## Wherein R is defined as hereinafter, having a blocking activity on .beta.-adrenergic nerves, a novel intermediate useful for synthesis thereof and processes for preparing the same are disclosed.|
|Inventor(s):||Tamura; Yasumitsu (Takarazuka, JA), Nakagawa; Kazuyuki (Tokushima, JA), Yoshizaki; Shiro (Komatsujima, JA), Murakami; Nanami (Tokushima, JA)|
|Assignee:||Otsuka Pharmaceutical (Tokyo, JA)|
1. A 3,4-Dihydrocarbostyril derivative represented by the formula ##SPC6##
and the pharmaceutically acceptable acid addition salts thereof, wherein R represents a straight or branched alkyl group having 1 to 4 carbon atoms.
2. 5-(2-Hydroxy-3-methylamino)propoxy-3,4-dihydrocarbostryil according to claim 1.
3. 5-(2-Hydroxy-3-ethylamino)propoxy-3,4-dihydrocarbostyril according to claim 1.
4. 5-(2-Hydroxy-3-propylamino)propoxy-3,4-dihydrocarbostyril according to claim 1.
5. 5-(2-Hydroxy-3-butylamino)propoxy-3,4-dihydrocarbostyril according to claim 1.
6. 5-(2-Hydroxy-3-tert-butylamino)propoxy-3,4-dihydrocarbostyril according to claim 5.
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