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Generated: August 20, 2017

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Title: Acylated derivatives of trp-met-asp-phe-NH.sub.2
Abstract:Acylated derivatives of L-tryptophanyl-L-methionyl-L-aspartyl-L-phenylalanine amide which are active in promoting the secretion of acidic gastric juice in mammals.
Inventor(s): Hardy; Paul Martin (Exeter, EN), Kenner; George Wallace (Liverpool, EN), Sheppard; Robert Charles (Liverpool, EN), Morley; John Selwyn (Liverpool, EN), MacLeod; John Keith (Liverpool, EN)
Assignee: Imperial Chemical Industries Limited (London, EN)
Application Number:04/462,107
Patent Claims: 1. N-t-Butyloxyca rbonyl-L-alanyl-L-phenylalanyl-L-isoleucylglycyl-L-tryptophanyl-L-methionyl -L-aspartyl-L-phenylalanine amide and the acid addition salts thereof.

2. N-Acetyl-L-tryptophanyl-L-methionyl-L-aspartyl-L-phenylalanine amide and the acid addition salts thereof.

3. N-t-Butyloxycarbonyl-.beta.-al anyl-L-tryptophanyl-L-methionyl-L-aspartyl-L-phenylalanine amide and the acid addition salts thereof.

4. N-Pivaloyl-.beta.-alanyl-L -tryptophanyl-L-methionyl-L-aspartyl-L-phenylalanine amide and the acid addition salts thereof.

5. N-Carbamoyl-L-tryptophanyl-L-methionyl-L-aspartyl-L-phenylalanine amide and acid addition salts thereof.
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Serving 500+ biopharmaceutical companies globally:

Fuji
US Department of Justice
Harvard Business School
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Healthtrust
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