DrugPatentWatch Database Preview
« Back to Dashboard
Summary for Patent: 3,883,545
|Abstract:||New 1-hydroxy-2-pyridones of the general formula ##SPC1## In which R.sub.1 is alkyl of 1 to 17 carbon atoms, cycloalkyl of 5 to 8 carbon atoms, cyclohexylalkyl or phenalkyl both having 1 to 3 carbon atoms in the alkylene chain or .alpha.-furyl, all of which may be substituted by halogen and R.sub.2 to R.sub.4 are hydrogen or lower alkyl or 2 adjacent substituents together form a trimethylene or tetramethylene chain, and in which R.sub.1 to R.sub.4 together contain at least 2 carbon atoms, are prepared by contacting unsaturated .delta.-keto esters or mixtures thereof with hydroxylamine and subjecting the products to cyclization. The compounds exhibit antimycotic properties.|
|Inventor(s):||Lohaus; Gerhard (Kelkheim/Taunus, DT), Dittmar; Walter (Hofheim/Taunus, DT)|
|Assignee:||Hoechst Aktiengesellschaft (Frankfurt am Main, DT)|
1. A 1-hydroxy-2-pyridone of the formula ##SPC5##
wherein R.sub.1 is alkyl of 7 to 11 carbon atoms, cycloalkyl of 5 to 8 carbon atoms, cyclohexylalkyl or phenylalkyl both having 1 to 3 carbon atoms in the alkylene chain and wherein phenylalkyl may be substituted in the phenyl ring by one chlorine or fluorine atom, or .alpha.-furyl, and R.sub.3 and R.sub.4 are hydrogen or lower alkyl.
2. A compound of the formula II ##SPC6##
in which R.sub.1 is alkyl containing 7 to 11 carbon atoms and R.sub.3 is lower alkyl.
For more information try a trial or see the plans and pricing
Serving hundreds of leading biopharmaceutical companies globally:
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.