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Claims for Patent: 3,761,590

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Claims for Patent: 3,761,590

Title: SILVER SULFADIAZINE USED IN THE TREATMENT OF BURNS
Abstract:Silver sulfadiazine has been found to be useful in burn therapy by applying to the affected surface silver sulfadiazine, preferably dispersed in a water-dispersible hydrophilic carrier.
Inventor(s): Fox, Jr.; Charles L. (New York, NY)
Assignee: Research Corporation (New York, NY)
Application Number:05/038,031
Patent Claims: 1. A method of treating burns in man and animal which comprises topically applying an effective anti-bacterial amount of silver sulfadiazine to the affected surface.

2. A method in accordance with claim 1 wherein said silver sulfadiazine is applied as a dispersion in a water-dispersible, hydrophilic carrier.

3. A method in accordance with claim 1 wherein said silver sulfadiazine is applied as a dispersion in a semi-soft or cream-like, water-dispersible or water-soluble oil-in-water emulsion carrier.

4. A method in accordance with claim 1 wherein said silver sulfadiazine is applied as a dispersion in a water-dispersible, hydrophilic carrier, said carrier containing an amount in the range from about 0.1 to about 10 percent by weight of silver sulfadiazine dispersed therein.

5. A method in accordance with claim 1 wherein silver sulfadiazine is applied as a dispersion in a semi-soft or cream-like, water-dispersible or water-soluble oil-in-water emulsion carrier, said carrier containing an amount in the range from about 0.1 to about 10 percent by weight of silver sulfadiazine dispersed therein.

6. A method in accordance with claim 2 wherein said dispersion consists essentially of 0-25 percent by weight petrolatum, 7-45 percent by weight of a long chain fatty alcohol having a carbon atom content in the range C.sub.16 -C.sub.22, 0.1-10 percent by weight silver sulfadiazine, 4-16 percent by weight of a non-ionic emulsifying agent, 7-40 percent by weight of a humectant selected from the group consisting of propylene glycol, sorbitol and glycerin, 0-15 percent by weight of an emollient and an amount of water, when required, sufficient to bring the total of the percentages of the above-identified components to 100 percent.
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