Claims for Patent: 3,732,340
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Summary for Patent: 3,732,340
| Title: | N',o-propylene phosphoric acid ester diamides |
| Abstract: | THERE ARE PROVIDED NEW N-SUBSTITUTED AMIDES AND ESTERAAMIDES OF PHOSPHORIC ACID OF THE FORMULA I: O<(-P(=O)(-X2)-N(-R1)-(C(-Z)2)M-) WHEREIN R1 IS A LOWER ALKYL GROUP HAVING FROM 1 TO 4 CARBON ATOMS BEING SUBSTITUTED WITH ONE OR SEVERAL HALOGEN ATOMS, Z IS HYDROGEN OR A LOWER ALKYL GROUP HAVING FROM 1 TO 4 CARBON ATOMS, M IS 2 OR 3 AND X2 IS THE ETHYLENE IMINO GROUP OR THE GROUP HAVING THE FORMULA: CL-(-C(-Z)2)M-N-R WHEREIN R IS HYDROGEN OR A LOWER ALKYL GROUP HAVING FROM 1 TO 4 CARBON ATOMS WHICH MAY BE SUBSTITUTED WITH A CHLORINE ATOM OR A HYDROXY GROUP, AND Z AND M HAVE THE ABOVE-GIVEN MEANING. EACH OF THESE PRODUCTS IS USEFUL AS A CYTOSTATICALLY EFFECTIVE COMPOUND AND IS USED IN THE MANNER EXEMPLIFIED HEREINAFTER WITH RESPECT TO TEST ANIMALS, E.G. RATS, ACCORDING TO KNOWN TECHNIQUES FOR ADMINISTERING TEST DOSAGES. |
| Inventor(s): | H Arnold, N Brock, F Bourseaux, H Bekel |
| Assignee: | ASTA WERKE AG DT, Asta Medica GmbH |
| Application Number: | US00106569A |
| Patent Claims: |
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