|Title:|| 15-METHYL AND 15-ETHYL PROSTAGLANDIN ANALOGS|
|Abstract:||Prostaglandin E and F compounds with a methyl or an ethyl substituent at the C-15 position are disclosed. These are useful for the same pharmacological purposes as the unsubstituted prostaglandins.|
|Inventor(s):|| Bundy; Gordon L. (Kalamazoo Township, Kalamazoo County, MI) |
|Assignee:|| The Upjohn Company (Kalamazoo, MI) |
1. An optically active compound of the formula: ##SPC19##
or a racemic compound of that formula and the mirror image thereof, wherein R.sub.1 is hydrogen, alkyl of one to eight carbon atoms, inclusive, or a pharmacologically acceptable cation, and wherein R.sub.2 is methyl or ethyl.
2. 15-Methyl-PGF.sub. 2.sub..alpha., an optically active compound according to claim 1 wherein R.sub.1 is hydrogen and R.sub.2 is methyl.
3. Racemic 15-methyl-PGF.sub.2.sub..alpha., a compound according to claim 1 wherein R.sub.1 is hydrogen and R.sub.2 is methyl.