Claims for Patent: 3,706,789

Summary for Patent: 3,706,789

Title:	Pgf{11 {60
Abstract:	The prostaglandins PGF2 Alpha and PGF2 Beta , and their salts, esters, and alkanoates are disclosed. These novel compounds are useful for a variety of pharmacological purposes, including use as smooth muscle stimulants and as cardiovascular agents.
Inventor(s):	Sune Bergstrom, Jan Sjovall
Assignee:	Individual
Application Number:	US115111A
Patent Claims:	2. A compound according to claim 1 wherein R1 is alkyl of one to eight carbon atoms, inclusive, and all R2 are hydrogen. 3. A compound according to claim 1 wherein R1 is methyl and all R2 are hydrogen. 4. A compound according to claim 1 wherein R1 is alkyl of one to eight carbon atoms, inclusive, and wherein all R2 are lower alkanoyl. 5. A compound according to claim 1 wherein R1 is alkyl of one to eight carbons, inclusive and wherein all R2 are acetyl. 6. A compound according to claim 1 wherein R1 is methyl and all R2 are acetyl. 7. A compound of the formula: wherein R3 is hydrogen or a pharmacologically acceptable cation, and wherein R4 is lower alkanoyl. 8. A compound according to claim 7 wherein R3 is hydrogen. 9. A compound in claim 8 wherein R4 is acetyl. 10. A compound of the formula: wherein R3 is hydrogen or a pharmacologically acceptable cation, said compound being essentially free of pyrogens, antigens, proteins, enzymes, cellular material, and other organic acids or salts thereof. 11. A compound according to claim 10 wherein R3 is hydrogen, said compound being 7-(3 Alpha ,5 Alpha -dihydroxy-2 Beta -((3S)-3-hydroxy-trans-1-octenyl)-1 Alpha -cyclopentyl)-cis-5-heptenoic acid. 12. A compound according to claim 10 wherein R3 is a pharmacologically acceptable cation, said compound being a salt of 7-(3 Alpha ,5 Alpha -dihydroxy)-2 Beta -((3S)-3-hydroxy-trans-1-octenyl)-1 Alpha -cyclopentyl)-cis-5-heptenoic acid.