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Last Updated: December 17, 2025

Claims for Patent: 3,674,836


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Summary for Patent: 3,674,836
Title:2,2-dimethyl-{11 -aryloxy-alkanoic acids and salts and esters thereof
Abstract:A series of 2,2-dimethyl- omega -phenoxyalkanoic acids and 2,2dimethyl- omega -(disubstituted phenoxy)alkanoic acids having 3 to 6 methylene groups between the phenoxy group or 0 phenoxy group and the carbon atom substituted by two methyl groups; and their salts and esters. The compounds reduce serum triglyceride levels and can be produced by (a) reacting an alkali metal derivative of an isobutyric acid, salt, or ester with a phenoxyalkyl halide or a disubstituted phenoxyalkyl halide; (b) esterifying a carboxylic acid; or (c) hydrolyzing a carboxylate ester.
Inventor(s):Paul L Creger
Assignee: Parke Davis and Co LLC
Application Number:US819126A
Patent Claims: 2. A compound according to claim 1 wherein R represents hydrogen.

3. A compound according to claim 1 wherein R represents lower alkyl.

4. A compound according to claim 1 which is 2,2-dimethyl-5-phenoxyvaleric acid.

5. A compound according to claim 1 which is 2,2-dimethyl-6-phenoxyhexanoic acid.

6. A compound according to claim 1 which is 2,2-dimethyl-5-(2,5-xylyloxy)valeric acid.

7. A compound according to claim 1 which is 2,2-dimethyl-5-(3,5-xylyloxy)valeric acid.

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