Claims for Patent: 3,553,212
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Summary for Patent: 3,553,212
| Title: | 2-beta,16-beta-diamino-androstanes |
| Abstract: | 2B, 16B-DIAMINO-ANDROSTANE COMPOUNDS OXYGENATED IN THE 3- AND 17-POSITIONS, WHEREIN THE AMINO GROUPS MAY BE DIALKYLAMINO AND HETEROCYCLIC AMINO GROUPS, AND THEIR ACID ADDITION SALTS AND QUATERNARY AMMONIUM SALTS, ARE PREPARED BY REACTING A 16A, 17A-OXIDO-, OR A 16-KETO-STEROID WITH AN AMINE AT ELEVATED TEMPERATURE AND PRESSURE, FOLLOWED BY REDUCTION TO THE CORRESPONDING 17B-HYDROXY DERIVATIVE. THE COMPOUNDS OF THE INVENTION ARE HIGHLY ACTIVE NEUROMUSCULAR BLOCKING AGENTS AND HAVE A STRONG INFLUENCE ON THE AUTONOMIC NERVOUS SYSTEM. |
| Inventor(s): | Colin Leslie Hewett, David Samuel Savage |
| Assignee: | Organon NV , Organon Inc |
| Application Number: | US722545A |
| Patent Claims: |
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