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Last Updated: December 12, 2025

Claims for Patent: 12,396,947

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Summary for Patent: 12,396,947

Title:	Methotrexate composition
Abstract:	A Methotrexate composition for oral administration is provided comprising a pharmaceutically acceptable salt of Methotrexate and an aqueous carrier agent. The Methotrexate salt is substantially or completely soluble in the aqueous carrier agent, forming an aqueous solution. There is also provided a method of manufacturing a Methotrexate composition for oral administration, comprising mixing a pharmaceutically acceptable salt of Methotrexate with an aqueous carrier agent until the Methotrexate salt is substantially or completely soluble in the carrier agent to form an aqueous solution.
Inventor(s):	Carl Tierney, Stacey Powell, Peter Braybrooke, Geraint Jones
Assignee:	Rosemont Pharmaceuticals Ltd
Application Number:	US18/130,530
Patent Claims:	1. A methotrexate composition for oral administration, said composition consisting of: methotrexate or a salt thereof; one or more buffer agents to adjust the pH of the composition, wherein the pH of the composition is 6 to 7; one or more preserving agents; one or more agents selected from flavouring compounds and sweetening agents; and purified water, wherein the composition is a solution.

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