Claims for Patent: 12,377,176
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Summary for Patent: 12,377,176
| Title: | Cancer diagnostic imaging agents |
| Abstract: | The present invention relates to a ligand-SIFA-chelator conjugate, comprising, within a single molecule three separate moieties: (a) one or more ligands which are capable of binding to PSMA, (b) a silicon-fluoride acceptor (SIFA) moiety which comprises a covalent bond between a silicon atom and a fluorine atom, and (c) one or more chelating groups, containing a chelated nonradioactive cation. |
| Inventor(s): | Alexander Josef Wurzer, Hans-Jürgen Wester, Matthias Johannes Eiber |
| Assignee: | Technische Universitaet Muenchen Klinikum Rechts Der Isar , Technische Universitaet Muenchen , Klinikum Rechts der Isar der Technischen Universitaet Muenchen |
| Application Number: | US17/427,006 |
| Patent Claims: |
1. A compound having a chemical structure: or a pharmaceutically acceptable salt thereof. 2. A pharmaceutical or diagnostic composition comprising or consisting of one or more conjugates in accordance with claim 1. 3. A method of imaging and/or diagnosing cancer comprising administering a conjugate according to claim 1 to a patient in need thereof. 4. A method of treating cancer comprising administering a conjugate according to claim 1 to a patient in need thereof. 5. A method of reducing neoangiogenesis/angiogenesis comprising administering a conjugate according to claim 1 to a patient in need thereof. 6. A method according to claim 4 wherein the cancer is prostate, breast, lung, colorectal or renal cell carcinoma. |
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ISSN: 2162-2639
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Friedman, Yali. "DrugPatentWatch" DrugPatentWatch, thinkBiotech, 2025, www.DrugPatentWatch.com.
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