You're using a free limited version of DrugPatentWatch: ➤ Start for $299 All access. No Commitment.

Last Updated: December 12, 2025

Claims for Patent: 12,280,024

✉ Email this page to a colleague

« Back to Dashboard

Summary for Patent: 12,280,024

Title:	Epinephrine formulations
Abstract:	Pharmaceutical compositions comprising epinephrine, methods of administration, and methods of making the same. Compositions may comprise at least one of an active agent, a pH raising agent, an antioxidant, a transition metal complexing agent, a pH lowering agent, a tonicity regulating agent, optionally a preservative, and optionally a solvent.
Inventor(s):	Suketu Sanghvi, Vinayagam Kannan, Matthew Kenney
Assignee:	Endo Operations Ltd
Application Number:	US18/477,161
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 12,280,024
Patent Claims:	1. A composition comprising: in the range of about 0.75 to 1.25 mg/mL of epinephrine and/or salts thereof, in the range of about 6 to 8 mg/mL of a tonicity regulating agent, in the range of 2 and 15 mg/mL of tartaric acid, in the range of 1 and 5 mg/mL of sodium hydroxide, in the range of about 0.4 and 0.5 mg/mL of an antioxidant, in the range of about 0.001 to 0.010 mL/mL of a pH lowering agent, wherein the antioxidant comprises sodium bisulfite and/or sodium metabisulfite, and wherein the composition comprises about 3% or less total impurities after 6 months of storage at between 23° C. and 32° C. and between 55% RH and 70% RH. 2. The composition of claim 1, wherein the tonicity regulating agent comprises sodium chloride. 3. The composition of claim 1, wherein the pH lowering agent comprises hydrochloric acid. 4. The composition of claim 1, further comprising a solvent.

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. We do not provide individual investment advice. This service is not registered with any financial regulatory agency. The information we publish is educational only and based on our opinions plus our models. By using DrugPatentWatch you acknowledge that we do not provide personalized recommendations or advice. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.