Claims for Patent: 12,128,010

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Summary for Patent: 12,128,010

Title:	Semifluorinated compounds and their compositions
Abstract:	The present invention is directed to compositions comprising semifluorinated compounds and their use as medicaments for topical administration to the eye.
Inventor(s):	Dieter Scherer, Ralf GRILLENBERGER, Frank LÖSCHER, Hartmut Voss
Assignee:	Novaliq GmbH
Application Number:	US17/833,836
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 12,128,010
Patent Claims:	1. A composition comprising CF3(CF2)5(CH2)7CH3 and CF3—(CF2)5—CH(CH3)—(CH2)5—CH3. 2. The composition according to claim 1, comprising at least about 80 wt % of CF3(CF2)5(CH2)7CH3. 3. The composition according to claim 1, comprising up to about 25 wt % of CF3—(CF2)5—CH(CH3)—(CH2)5—CH3. 4. The composition according to claim 1, comprising about 97 wt % of CF3(CF2)5(CH2)7CH3 and up to about 3 wt % of CF3—(CF2)5—CH(CH3)—(CH2)5—CH3. 5. The composition according to claim 1, being formulated as a clear liquid solution. 6. The composition according to claim 1, being free of: (a) a polymer, (b) a perfluorinated compound, and/or (c) a dissolved pharmacologically active ingredient. 7. The composition of according to claim 1, having a dynamic viscosity of not more than 10 mPa·s, at ambient temperature and pressure. 8. The composition according to claim 1, wherein the composition has a refractive index between 1.30 and 1.35 at 20° C., as determined by a refractometer. 9. A kit comprising a composition comprising CF3(CF2)5(CH2)7CH3 and CF3—(CF2)5—CH(CH3)—(CH2)5—CH3 and a container for holding the composition. 10. The kit of claim 9, wherein the container comprises a dispensing means adapted for topical administration of the composition to a lacrimal sac, into a lower eyelid, to an eye surface, or to an ophthalmic tissue. 11. The kit of claim 10, wherein the dispensing means comprises a dropper which dispenses droplets having a volume of 8 to 15 μL. 12. The kit of claim 10, wherein the dispensing means comprises a dropper which dispenses droplets having a volume of 8 to 12 μL. 13. The kit of claim 10, wherein the dispensing means comprises a dropper which dispenses droplets having a volume of 10 μL.