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Last Updated: December 12, 2025

Claims for Patent: 11,833,248

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Summary for Patent: 11,833,248

Title:	Solid compositions comprising a GLP-1 agonist and a salt of N-(8-(2-hydroxybenzoyl)amino)caprylic acid
Abstract:	The invention relates to pharmaceutical compositions comprising a peptide, such as a GLP-1 peptide and a salt of N-(8-(2-hydroxybenzoyl)amino)caprylic acid. The invention further relates to processes for the preparation of such compositions, and their use in medicine.
Inventor(s):	Betty Lomstein Pedersen, Birgitte Nissen
Assignee:	Novo Nordisk AS
Application Number:	US16/570,723
Patent Claims:	1. A pharmaceutical composition consisting essentially of semaglutide, magnesium stearate, and sodium N-(8-(2-hydroxybenzoyl)amino)caprylate (SNAC), wherein the pharmaceutical composition comprises 2-5 mg of the magnesium stearate per 100 mg of the SNAC; and wherein the pharmaceutical composition does not comprise a binder or filler. 2. A method of treating diabetes, comprising administering to a subject in need thereof the pharmaceutical composition according to claim 1. 3. A method of reducing body weight, comprising administering to a subject in need thereof the pharmaceutical composition according to claim 1. 4. The method according to claim 2, wherein the subject is suffering from obesity. 5. The method according to claim 3, wherein the subject is suffering from obesity. 6. A pharmaceutical composition comprising semaglutide, magnesium stearate, and sodium N-(8-(2-hydroxybenzoyl)amino)caprylate (SNAC), wherein the pharmaceutical composition comprises 2-5 mg of the magnesium stearate per 100 mg of the SNAC, and wherein the SNAC constitutes at least 95% of the excipients of the composition. 7. A method of treating diabetes, comprising administering to a subject in need thereof the pharmaceutical composition according to claim 6. 8. The method according to claim 7, wherein the subject is suffering from obesity. 9. A method of reducing weight, comprising administering to a subject in need thereof the pharmaceutical composition according to claim 6. 10. The method according to claim 9, wherein the subject is suffering from obesity.

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