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Last Updated: December 17, 2025

Claims for Patent: 11,827,642

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Summary for Patent: 11,827,642

Title:	Compositions useful for treating disorders related to KIT
Abstract:	Compounds and compositions useful for treating disorders related to mutant KIT are described herein.
Inventor(s):	Brian L. Hodous, Joseph L. Kim, Kevin J. Wilson, Douglas Wilson, Yulian Zhang
Assignee:	Blueprint Medicines Corp
Application Number:	US17/983,747
Patent Claims:	1. A method of treating indolent systemic mastocytosis in a patient in need thereof, wherein the method comprises administering to the patient a therapeutically effective amount of a compound which is: or a pharmaceutically acceptable salt thereof. 2. The method of claim 1, wherein the patient is administered a pharmaceutical composition comprising a therapeutically effective amount of the compound or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier. 3. The method of claim 1, wherein the patient has a mutation in Exon 17 in KIT. 4. The method of claim 3, wherein the patient has a D816 mutation in Exon 17 in KIT. 5. The method of claim 4, wherein the D816 mutation is D816V. 6. The method of claim 1, wherein the patient is administered a therapeutically effective amount of the compound which is:

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