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Last Updated: December 12, 2025

Claims for Patent: 11,795,204

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Summary for Patent: 11,795,204

Title:	Glucagon analogues
Abstract:	The present invention relates to glucagon analogues and their medical use, for example in the treatment of hypoglycaemia. In particular, the present invention relates to stable glucagon analogues suitable for use in a liquid formulation.
Inventor(s):	Ditte Riber, Lise Giehm
Assignee:	Zealand Pharma AS
Application Number:	US16/566,992
Patent Claims:	1. A method of treating a subject suffering from hypoglycaemia comprising administering a therapeutically effective amount of the compound: (SEQ ID NO: 22) Hy-HSQGTFTSDYSKYLD-Aib-ARAEEFVKWLEST-OH, or pharmaceutically acceptable salt thereof to the subject. 2. The method of claim 1, wherein the hypoglycaemia is selected from the group consisting of: diabetic hypoglycaemia, acute insulin-induced hypoglycaemia, non-diabetic hypoglycaemia, reactive hypoglycaemia, fasting hypoglycaemia, drug-induced hypoglycaemia, alcohol-induced hypoglycaemia, gastric bypass-induced hypoglycaemia, and hypoglycaemia occurring during pregnancy. 3. The method of claim 2, wherein the hypoglycaemia is diabetic hypoglycaemia. 4. The method of claim 2, wherein the hypoglycaemia is acute insulin-induced hypoglycaemia. 5. The method of claim 2, wherein the hypoglycaemia is non-diabetic hypoglycaemia. 6. The method of claim 2, wherein the hypoglycaemia is reactive hypoglycaemia. 7. The method of claim 2, wherein the hypoglycaemia is fasting hypoglycaemia. 8. The method of claim 2, wherein the hypoglycaemia is drug-induced hypoglycaemia. 9. The method of claim 2, wherein the hypoglycaemia is alcohol-induced hypoglycaemia. 10. The method of claim 2, wherein the hypoglycaemia is gastric bypass-induced hypoglycaemia. 11. The method of claim 2, wherein the hypoglycaemia is hypoglycaemia occurring during pregnancy.

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