Claims for Patent: 11,369,567

Summary for Patent: 11,369,567

Title:	Aqueous suspension suitable for oral administration
Abstract:	The present invention provides liquid oral dosage form of lipid lowering agent suitable for oral administration to human or animals.
Inventor(s):	Sandip P. Mehta, Henil Alpeshbhai PATEL, Jayanta Kumar Mandal
Assignee:	Liqmeds Worldwide Ltd , FTF Pharma Pvt Ltd
Application Number:	US16/308,731
Patent Claims:	1. An aqueous suspension for oral administration, consisting of: atorvastatin in an amount of about 0.4% w/w; a suspending agent in an amount of about 2% w/w comprising carboxymethyl cellulose sodium in an amount of about 0.7% w/w and magnesium aluminum silicate in an amount of about 1.3% w/w; a preservative in an amount of from 0.01% w/w to 0.5% w/w; a sweetener in an amount of about 0.1% w/w to 2% w/w; a flavoring agent in an amount of from 0.01 to 2.0% w/w; and a water vehicle; wherein the atorvastatin has a d90 particle size of about 6 μm. 2. The aqueous suspension of claim 1, wherein the preservative is selected from the group consisting of alcohol, benzyl alcohol, chlorobutol, chlorocresol, an alkyl esters of paraben, phenol, phenyl ethanol, sodium benzoate, propylene glycol, chloroform, and a combination thereof. 3. The aqueous suspension of claim 1, wherein the preservative comprises an alkyl ester of paraben. 4. The aqueous suspension of claim 1, wherein the pH of the aqueous suspension ranges from 6 to 9. 5. The aqueous suspension of claim 1, wherein a dose of the aqueous suspension comprising 40 mg of atorvastatin has a T/R ratio of from 90% to 110%, wherein T is a Cmax-value of the dose after administration to a human, and wherein R is a Cmax-value of a tablet comprising 40 mg atorvastatin after administration to the human.