Claims for Patent: 11,179,328

Summary for Patent: 11,179,328

Title:	Compositions and methods for the treatment of presbyopia
Abstract:	The invention provides compositions and methods for the treatment of presbyopia. The compositions preferably comprise aceclidine. The compositions optionally contain a surfactant and a viscosity agent.
Inventor(s):	Gerald Horn
Assignee:	Lenz Therapeutics Operations Inc
Application Number:	US16/747,070
Patent Claims:	1. A method of treating presbyopia comprising administering to a subject in need thereof an ophthalmological composition comprising aceclidine as the only active agent. 2. A method of treating presbyopia comprising administering to a subject in need thereof an ophthalmological composition comprising aceclidine as the only active agent and a viscosity agent. 3. A method of treating presbyopia comprising administering a composition comprising aceclidine as the only active agent and one or more nonionic surfactants to a subject in need thereof. 4. The method of claim 3, wherein aceclidine is at a concentration from about 0.25% to about 2.5% w/v, wherein w/v denotes weight by total volume of the composition. 5. The method of claim 3, wherein aceclidine is at a concentration from about 0.75% to about 2.5% w/v. 6. A method of treating low regular astigmatism, low or high irregular astigmatism, keratoconic ectasia, night vision halos/starbursts, night vision reduced contrast, and low myopia, or hyperopia, with or without astigmatism, comprising administering to a subject in need thereof an ophthalmological composition comprising aceclidine as the only active agent and a viscosity agent.