Claims for Patent: 10,905,827

Summary for Patent: 10,905,827

Title:	Injection device with cammed ram assembly
Abstract:	An exemplary embodiment of injector includes a trigger mechanism, an energy source, and a user-operable firing-initiation member. The trigger member can include a trigger member having a retainer portion, and a ram assembly having a ram configured to pressurize a medicament container for expelling a medicament therefrom and a trigger engagement member configured to engage the retainer portion of the trigger member in a pre-firing condition. The energy source can be associated with the ram for powering the ram to expel the medicament, and the user-operable firing-initiation member can be operable for causing an axial rotation between the trigger engagement member and the retainer portion from the pre-firing condition to a firing condition in which the trigger engagement member is released from the retainer portion to allow the energy source to fire the ram.
Inventor(s):	Kramer; Thomas (Andover, MN), Rust; Matthew H. (Hudson, WI), Goudreau; Paul M. (St. Paul, MN), Hoeft; Peter A. (Seattle, WA), Sund; Julius C. (Plymouth, MN), Sadowski; Peter L. (Woodbury, MN)
Assignee:	Antares Pharma, Inc. (Ewing, NJ)
Application Number:	15/157,851
Patent Claims:	1. An injector, comprising: an injector housing; a container support at least partially within the injector housing, the container support including a projection configured to fix the container support relative to the injector housing; a medicament container associated with the container support; a trigger mechanism including: a trigger member having a retainer portion, and a ram assembly having a ram configured to pressurize the medicament container for expelling a medicament therefrom, the ram assembly further having a trigger engagement member configured to engage the retainer portion of the trigger member in a pre-firing condition; an energy source associated with the ram for powering the ram to expel the medicament; and a user-operable firing-initiation member operable for causing relative movement between the trigger engagement member and the retainer portion from the pre-firing condition to a firing condition in which the trigger engagement member is released from the retainer portion to allow the energy source to fire the ram, wherein the ram assembly includes an opening extending radially through a sidewall of the ram assembly, the opening defined by an opening sidewall and configured to receive at least a portion of the user-operable firing-initiation member. 2. The injector of claim 1, wherein the user-operable firing-initiation member includes a skin-contacting member disposed at a distal end of the injector, the skin-contacting member configured to move proximally with respect to the injector housing when a force is applied to the skin-contacting member, and wherein the user-operable firing-initiation member is associated with the trigger mechanism and is configured to cause axial rotation between the trigger engagement member and the retainer portion from the pre-firing condition to the firing condition upon a proximal movement of the skin-contacting member with respect to the injector housing. 3. The injector of claim 2, wherein the skin-contacting member comprises a first cam, and the ram assembly comprises a second cam, the first cam being operatively associated with the second cam for camming the second cam such that the proximal movement of the skin-contacting member with respect to the injector housing is configured to rotate the ram assembly with respect to the retainer portion so as to position the ram assembly in the firing condition. 4. The injector of claim 1, wherein the user-operable firing-initiation member comprises a skin-contacting member which includes a needle guard that is retractable and is configured to expose a needle connected to the medicament container upon proximal movement of the skin-contacting member. 5. The injector of claim 4, wherein the needle is in fluid communication with the medicament container for injecting the medicament expelled therefrom during firing. 6. The injector of claim 4, wherein the energy source and the needle are configured for jet injecting the medicament through the needle. 7. The injector of claim 6, wherein the energy source is configured to pressurize the medicament to between 90 p.s.i. and 500 p.s.i. to jet inject the medicament. 8. The injector of claim 6, wherein the energy source and the needle are configured for injecting the medicament at an average velocity of at least 1,000 cm/sec within the needle. 9. The injector of claim 1, wherein: the trigger engagement member and the ram are in fixed association, such that rotation of the trigger engagement member rotates the ram; and the ram assembly is associated with the user-operable firing-initiation member such that operation of the user-operable firing-initiation member rotates the ram assembly within the injector housing to the firing condition. 10. The injector of claim 9, wherein the trigger mechanism comprises a ram holding member that retains the ram assembly against action of the energy source in the pre-firing position, the retainer portion retaining the trigger engagement member, wherein the trigger engagement member is prevented from firing by the ram holding member. 11. The injector of claim 10, wherein in the firing condition, the trigger engagement member is disengaged from the retainer portion, and the energy source overcomes an engagement between the trigger engagement member and the ram holding member. 12. The injector of claim 10, wherein the ram holding member includes a projection that includes a bulge and a groove engaged with the trigger engagement member, and wherein the retainer portion is configured to at least temporarily retain engagement of the trigger engagement member with the bulge and the groove in the pre-firing condition. 13. The injector of claim 1, wherein the ram assembly is of unitary construction. 14. The injector of claim 1, wherein the ram assembly is configured to engage the container support to lock-out the injector after an injection. 15. The injector of claim 14, wherein proximal movement of the user-operable firing-initiation member is blocked by the ram assembly when the injector is locked-out. 16. The injector of claim 1, wherein a pre-firing color gamut is visible from an exterior of the injector in the pre-firing condition, the injector further comprising: a window in the injector housing; and an indicator having an indicator color that is absent from the pre-firing color gamut, which color is hidden from view within the injector housing in the pre-firing condition, wherein in the firing condition, the indicator color is visible through the window from the exterior of the injector for indicating that the injector has been fired. 17. The injector of claim 16, wherein the ram assembly includes the indicator. 18. The injector of claim 17, wherein the ram assembly entirely occludes the window after the injector has been fired. 19. The injector of claim 1, wherein the medicament comprises testosterone. 20. The injector of claim 1, wherein the user-operable firing-initiation member includes a locking projection configured to engage the opening sidewall wherein the locking projection engaged with the opening sidewall prevents movement of the user-operable firing-initiation member relative to the container support. 21. The injector of claim 1, wherein the container support includes a coupling arrangement configured to releasably couple to a cap. 22. The injector of claim 1, wherein the trigger engagement member radially flexes from a first position to a second position as the trigger engagement member moves from the pre-firing condition to the firing condition.