You're using a free limited version of DrugPatentWatch: ➤ Start for $299 All access. No Commitment.

Last Updated: December 13, 2025

Claims for Patent: 10,864,175

✉ Email this page to a colleague

« Back to Dashboard

Summary for Patent: 10,864,175

Title:	Eutectic formulations of cyclobenzaprine hydrochloride and amitriptyline hydrochloride
Abstract:	The present invention relates to pharmaceutical compositions and methods of manufacturing the same, comprising a eutectic of Cyclobenzaprine HCl and mannitol or Amitriptyline HCl and mannitol.
Inventor(s):	Marino Nebuloni, Patrizia Colombo
Assignee:	Tonix Pharma Holdings Ltd , Redox SRL
Application Number:	US16/140,090
Patent Claims:	1. A eutectic of Cyclobenzaprine HCl and β-mannitol comprising 75%±2% cyclobenzaprine HCl and 25%±2% β-mannitol by weight. 2. The eutectic of claim 1, wherein the Cyclobenzaprine HCl:β-mannitol molar ratio is 1.76±0.1. 3. The eutectic of claim 1 or 2, wherein the Cyclobenzaprine HCl is micronized Cyclobenzaprine HCl. 4. The eutectic of any one of claim 1-3, wherein the eutectic melts at 143.6±3° C.

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. We do not provide individual investment advice. This service is not registered with any financial regulatory agency. The information we publish is educational only and based on our opinions plus our models. By using DrugPatentWatch you acknowledge that we do not provide personalized recommendations or advice. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.