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Last Updated: December 12, 2025

Claims for Patent: 10,851,091

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Summary for Patent: 10,851,091

Title:	Benzoxazepin oxazolidinone compounds and methods of use
Abstract:	Described herein are benzoxazepin oxazolidinone compounds with phosphoinositide-3 kinase (PI3K) modulation activity or function having the Formula I structure:
Inventor(s):	Marie-Gabrielle Braun, Emily Hanan, Steven T. Staben, Robert Andrew Heald, Calum Macleod, Richard Elliott
Assignee:	Genentech Inc
Application Number:	US16/140,392
Patent Claims:	1. A compound of: or a pharmaceutically acceptable salt thereof. 2. A pharmaceutical composition comprising a compound of claim 1, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, glidant, diluent, or excipient. 3. The pharmaceutical composition of claim 2, wherein the pharmaceutically acceptable carrier, glidant, diluent, or excipient is selected from the group consisting of silicon dioxide, powdered cellulose, microcrystalline cellulose, metallic stearates, sodium aluminosilicate, sodium benzoate, calcium carbonate, calcium silicate, corn starch, magnesium carbonate, asbestos free talc, stearowet C, starch, starch 1500, magnesium lauryl sulfate, magnesium oxide, and combinations thereof.

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