Claims for Patent: 10,342,780

Summary for Patent: 10,342,780

Title:	Compounds useful as kinase inhibitors
Abstract:	This invention relates to novel compounds. The compounds of the invention are tyrosine kinase inhibitors. Specifically, the compounds of the invention are useful as inhibitors of Bruton's tyrosine kinase (BTK). The invention also contemplates the use of the compounds for treating conditions treatable by the inhibition of Bruton's tyrosine kinase, for example cancer, lymphoma, leukemia and immunological diseases.
Inventor(s):	Nicolas Guisot
Assignee:	Loxo Oncology Inc
Application Number:	US16/109,162
Patent Claims:	1. A compound selected from the group consisting of: or a pharmaceutically acceptable salt thereof. 2. The compound of claim 1, wherein the compound is or a pharmaceutically acceptable salt thereof. 3. The compound of claim 1, wherein the compound is or a pharmaceutically acceptable salt thereof. 4. The compound of claim 1, wherein the compound is or a pharmaceutically acceptable salt thereof. 5. The compound of claim 1, wherein the compound is or a pharmaceutically acceptable salt thereof. 6. The compound of claim 1, wherein the compound is or a pharmaceutically acceptable salt thereof. 7. The compound of claim 1, wherein the compound is or a pharmaceutically acceptable salt thereof. 8. The compound of claim 1, wherein the compound is or a pharmaceutically acceptable salt thereof. 9. The compound of claim 1, wherein the compound is or a pharmaceutically acceptable salt thereof. 10. The compound of claim 1, wherein the compound is or a pharmaceutically acceptable salt thereof. 11. The compound of claim 1, wherein the compound is selected from the group consisting of: 12. The compound of claim 1, wherein the compound is in the form of a pharmaceutically acceptable salt. 13. A pharmaceutical composition comprising a compound selected from the group consisting of: or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable excipient. 14. The pharmaceutical composition of claim 13, wherein the compound is or a pharmaceutically acceptable salt thereof. 15. The pharmaceutical composition of claim 13, wherein the compound is or a pharmaceutically acceptable salt thereof. 16. The pharmaceutical composition of claim 13, wherein the compound is or a pharmaceutically acceptable salt thereof. 17. The pharmaceutical composition of claim 13, wherein the compound is or a pharmaceutically acceptable salt thereof. 18. The pharmaceutical composition of claim 13, wherein the compound is or a pharmaceutically acceptable salt thereof. 19. The pharmaceutical composition of claim 13, wherein the compound is or a pharmaceutically acceptable salt thereof. 20. The pharmaceutical composition of claim 13, wherein the compound is or a pharmaceutically acceptable salt thereof. 21. The pharmaceutical composition of claim 13, wherein the compound is or a pharmaceutically acceptable salt thereof. 22. The pharmaceutical composition of claim 13, wherein the compound is or a pharmaceutically acceptable salt thereof. 23. The pharmaceutical composition of claim 13, wherein the compound is selected from the group consisting of: 24. The composition of claim 13, wherein the compound is in the form of a pharmaceutically acceptable salt.