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Last Updated: December 12, 2025

Claims for Patent: 10,174,061

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Summary for Patent: 10,174,061

Title:	Carbidopa and L-dopa prodrugs and methods of use
Abstract:	The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.
Inventor(s):	Benoit CARDINAL-DAVID, Vincent S. Chan, Brian P. ENRIGHT, Ye Huang, Alexander D. HUTERS, Russell C. Klix, Scott W. KRABBE, Philip R. Kym, Yanbin Lao, Xiaochun Lou, Sean E. Mackey, Mark A. Matulenko, Peter T. Mayer, Christopher P. Miller, James Stambuli, Eric A. Voight, Zhi Wang, Geoff G. Zhang, Valentino J. Stella
Assignee:	AbbVie Inc
Application Number:	US15/715,245
Patent Claims:	1. An aqueous pharmaceutical composition comprising: (a) a first compound corresponding in structure to Formula (I)-b: or a pharmaceutically acceptable salt thereof and, (b) a second compound corresponding in structure Formula (II)-b: or a pharmaceutically acceptable salt thereof; wherein the pharmaceutical composition is for subcutaneous administration. 2. A method of treating Parkinson's disease comprising administering to a subject in need thereof a therapeutically effective amount of the pharmaceutical composition according to claim 1. 3. The method of claim 2, further comprising administering another anti-Parkinson's agent to the subject. 4. A kit comprising the pharmaceutical composition of claim 1.

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