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Summary for Patent: 10,080,733
|Title:||Prodrugs of fumarates and their use in treating various diseases|
|Abstract:||The present invention provides compounds of formula (I), and pharmaceutical compositions thereof. ##STR00001##|
|Inventor(s):||Zeidan; Tarek A. (Lexington, MA), Duncan; Scott (Bedford, MA), Hencken; Christopher P. (Boston, MA), Wynn; Thomas Andrew (Lexington, MA), Sanrame; Carlos N. (Lexington, MA)|
|Assignee:||Alkermes Pharma Ireland Limited (Dublin, IE)|
|Patent Litigation and PTAB cases:||See patent lawsuits and PTAB cases for patent 10,080,733|
1. A crystalline form of a compound having the formula: ##STR00210## having an X-ray powder diffraction pattern comprising peaks, in terms of degrees 2-theta.+-.0.2 degrees, at
11.6, 21.0, 24.3, 27.4, and 27.9 when using a Cu X-ray source.
2. A pharmaceutical composition comprising a crystalline form of claim 1 and a pharmaceutically acceptable carrier.
3. A method of treating multiple sclerosis in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a crystalline form of claim 1.
4. A method of treating multiple sclerosis in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a composition of claim 2.
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