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Last Updated: March 29, 2024

Claims for Patent: 10,080,733


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Summary for Patent: 10,080,733
Title:Prodrugs of fumarates and their use in treating various diseases
Abstract: The present invention provides compounds of formula (I), and pharmaceutical compositions thereof. ##STR00001##
Inventor(s): Zeidan; Tarek A. (Lexington, MA), Duncan; Scott (Bedford, MA), Hencken; Christopher P. (Boston, MA), Wynn; Thomas Andrew (Lexington, MA), Sanrame; Carlos N. (Lexington, MA)
Assignee: Alkermes Pharma Ireland Limited (Dublin, IE)
Application Number:15/782,128
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 10,080,733
Patent Claims: 1. A crystalline form of a compound having the formula: ##STR00210## having an X-ray powder diffraction pattern comprising peaks, in terms of degrees 2-theta.+-.0.2 degrees, at 11.6, 21.0, 24.3, 27.4, and 27.9 when using a Cu X-ray source.

2. A pharmaceutical composition comprising a crystalline form of claim 1 and a pharmaceutically acceptable carrier.

3. A method of treating multiple sclerosis in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a crystalline form of claim 1.

4. A method of treating multiple sclerosis in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a composition of claim 2.

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