Claims for Patent: 10,016,403

Summary for Patent: 10,016,403

Title:	Sublingual fentanyl spray
Abstract:	The present invention is directed to sublingual formulations containing fentanyl, a pharmaceutically acceptable salt thereof, or derivative thereof, suitable for administration to a patient, and methods for treatment with the formulations.
Inventor(s):	Kottayil; S. George (Long Grove, IL), Goskonda; Venkat R. (Phoenix, AZ), Zhu; Zhongyuan (Vernon Hills, IL), Kattookaran; Linet (Mount Prospect, IL), Parikh; Neha (Chicago, IL)
Assignee:	INSYS DEVELOPMENT COMPANY, INC. (Chandler, AZ)
Application Number:	15/478,430
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 10,016,403
Patent Claims:	1. A sublingual formulation comprising from about 0.1% to about 0.9% by weight fentanyl, a free base or a pharmaceutically acceptable salt thereof, or a fentanyl derivative selected from the group consisting of sufentanil, carfentanil, lofentanil and alfentanil, from about 20% to about 60% by weight ethanol and from about 1% to about 30% by weight propylene glycol. 2. The sublingual formulation of claim 1, wherein the concentration of ethanol is from about 50% to about 60% by weight.