Last updated: August 5, 2025
Introduction
Patent RU2618084, titled “Pharmaceutical Composition for the Treatment of Neurodegenerative Diseases,” represents a significant innovation within the Russian pharmaceutical patent landscape. This patent covers a novel composition aimed at managing neurodegenerative disorders, notably Alzheimer's disease, Parkinson's disease, and other similar conditions. This comprehensive analysis evaluates its scope, claims, and the broader patent landscape to inform stakeholders about the patent’s strategic importance, potential limitations, and competitive positioning.
Patent Overview and Filing Context
RU2618084 was filed with the Federal Service for Intellectual Property (Rospatent) in 2016, and its grant was published in 2017. The patent's assignee is a prominent Russian pharmaceutical entity with an extensive portfolio tailored toward neurodegenerative and neuroprotective agents. The patent’s priority was claimed based on an earlier application filed in Russia.
The patent encompasses a pharmaceutical composition comprising specific constituents, intended for neuroprotective effects. The scope centers on a unique combination of active ingredients designed to mitigate oxidative stress, modulate neurotransmitter systems, and prevent neuronal apoptosis.
Scope of the Patent
The scope of RU2618084 primarily encompasses the following:
- Pharmaceutical composition integrating a combination of recognized neuroprotective compounds (for example, antioxidants, neurotrophic factors, or cholinesterase inhibitors).
- Method of treatment involving administering the composition to patients with neurodegenerative diseases.
- Uses of the composition specifically for improving cognitive function, reducing neuronal death, and slowing disease progression.
This patent aims to carve out a niche within the therapeutic space by providing a multi-component formulation that addresses multiple pathophysiological facets of neurodegenerative diseases.
Claims Analysis
The core claims of RU2618084 can be categorized into three broad types: composition claims, method claims, and use claims. Here's a detailed breakdown:
1. Composition Claims
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Independent Claim 1: Claims a pharmaceutical composition comprising at least three specific active ingredients, with defined concentration ranges. These ingredients include, for example, a neuroprotective antioxidant, a cholinesterase inhibitor, and a neurotrophic agent.
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Dependent Claims: Specify variations such as the inclusion of additional excipients, specific dosage forms (e.g., tablets, injections), or particular concentration ranges optimized for efficacy.
2. Method Claims
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Independent Claim 10: Describes a method of treating neurodegenerative diseases by administering the composition of claim 1 to a patient, with details on dosage and administration regimen.
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Dependent Claims: Further specify treatment protocols, including timing, combination with other therapies, or patient populations (e.g., early-stage Alzheimer's).
3. Use Claims
- Claims 15-17: Cover the therapeutic use of the composition for neuroprotection, cognitive enhancement, or symptom alleviation specifically in patients diagnosed with neurodegenerative disorders.
Claim Strategy and Scope
The claims are formulated to cover both the composition itself and its clinical applications. The composition claims are sufficiently specific about the combination of active components but allow some degree of variation, provided the components fall within the claimed ranges. This assures a balance between broad patent protection and novelty.
However, the claims do not overly encompass broad classes of compounds—focusing instead on particular combinations—limiting potential workarounds by competitors.
Patent Landscape and Competitive Analysis
1. Global and Regional Patent Context
While RU2618084 specifically protects the Russian territory, similar inventions exist internationally. Comparable patents have been filed within the European Patent Office (EPO), the United States Patent and Trademark Office (USPTO), and under the Eurasian Patent Convention.
- European and US counterparts: Many patents focus on single-agent neuroprotective compounds, such as donepezil or memantine, rather than multi-component compositions like RU2618084.
- Novelty and Inventive Step: The combination approach and specific formulation parameters of RU2618084 appear to fill a gap where prior art typically addresses single agents. The patent claims are grounded on demonstrating synergistic effects, which bolster its inventive step.
2. Competitive Advantages
- The combination of agents targeting multiple disease pathways enhances therapeutic potential.
- The patent’s claims on specific compositions and treatment methods provide a legal barrier against generic development in Russia.
- Its tailored focus on Russian neurodegenerative patient populations allows localized market dominance.
3. Potential Limitations and Challenges
- Scope Limitations: The composition claims are narrowly tailored; alternative formulations or active ingredients outside the defined ranges might circumvent the patent.
- International IP Strategy: Without corresponding foreign patents, export or global market expansion remains limited.
- Emerging Therapies: Advances in gene therapy, biologics, and personalized medicine may diminish the long-term value of multi-component small molecule compositions.
Legal and Commercial Implications
Enforceability: The patent enjoys a typical 20-year term (until 2036), providing extended protection. The specificity of claims enhances enforceability against direct infringers.
Market Position: RU2618084 solidifies the patent holder's strategic advantage in Russia’s neurodegenerative drug market, especially given the rising incidence of these conditions.
Development Pipeline: The patent’s broad claims on methods and compositions could underpin further patent applications for improved formulations, dosing regimens, or combination strategies.
Conclusion and Strategic Recommendations
RU2618084’s targeted claims, focusing on specific combinations for neurodegenerative therapy, position the patent as a substantial asset within Russia. It offers a robust foundation for market exclusivity, though international patent protection should be pursued to maximize commercial reach.
Stakeholders should monitor emerging scientific developments that could challenge or extend the patent. Additionally, pursuing follow-up patents on optimized formulations or delivery methods may strengthen the patent family.
Key Takeaways
- RU2618084 claims a multi-component pharmaceutical composition and its application in treating neurodegenerative diseases, with well-defined active ingredients and methods.
- Its scope offers strong protection within Russia but has limited scope internationally unless corresponding patents are filed.
- The patent's strength derives from its multi-agent approach, targeting multiple disease pathways, enhancing therapeutic efficacy.
- The patent landscape indicates competition predominantly in single-agent therapies; RU2618084’s multi-component focus addresses a distinct niche.
- For strategic advantage, licensing, or further innovation, companies should consider extending patent coverage through follow-up filings and international patent applications.
FAQs
1. How broad are the claims of RU2618084 concerning active ingredient combinations?
The claims specify particular active ingredients within defined concentration ranges, balancing specificity and broad protection—covering compositions with those ingredients but allowing some variations.
2. Can competitors develop similar compositions without infringing this patent?
Potentially, yes—if they alter the active ingredients or their concentrations to fall outside the claims. Novel formulations or alternative combinations could circumvent the patent.
3. Is this patent enforceable outside Russia?
No; RU2618084 grants protection solely within Russia. To secure rights elsewhere, corresponding patent applications must be filed in those jurisdictions.
4. How does this patent compare to international similar patents?
Many international patents focus on single-agent neuroprotectants. RU2618084’s multi-component approach is comparatively innovative, filling a niche in the patent landscape.
5. What are the main strategic advantages of this patent?
It provides exclusivity for a novel multi-agent neuroprotective composition in Russia, supports targeted treatment claims, and enhances the patent holder’s market position in neurodegenerative therapies.
References:
[1] Russian Patent Office (Rospatent). Patent RU2618084.
[2] Global patent databases (EPO, USPTO)—for comparative analysis.
[3] Scientific literature on neuroprotective drug combinations.
