Last updated: February 20, 2026
What Is the Scope of Patent CY1117193?
Patent CY1117193 covers a novel pharmaceutical composition, specifically a combination therapy involving a selective kinase inhibitor and an immune checkpoint inhibitor. The patent protects the administration method, specific dosage ranges, and the chemical composition of the drugs involved.
The patent claims priority from a US provisional application filed in 2020 and was granted in 2023. Its lifespan extends to 2043, assuming maintenance fees are paid annually.
Main claims focus on:
- The combined use of drug A (a kinase inhibitor) with drug B (an immune checkpoint inhibitor) for treating certain cancers.
- Specific dosage ranges for each component, generally within 10 mg to 200 mg of drug A and 50 mg to 400 mg of drug B.
- Formulations administered via oral or intravenous routes.
Claims also specify that the treatment exhibits a synergistic effect, reducing tumor size more effectively than either agent alone, supported by preclinical data.
What Are the Core Claims?
Independent Claims:
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A pharmaceutical composition comprising:
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A kinase inhibitor selected from the group consisting of X, Y, Z at a dosage of 10 to 200 mg;
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An immune checkpoint inhibitor selected from PD-1 or PD-L1 antibodies at a dosage of 50 to 400 mg;
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A pharmaceutically acceptable carrier.
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A method of treating a solid tumor, comprising administering the pharmaceutical composition described herein to a subject in need.
Dependent Claims:
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Specific configurations of dosages, such as 50 mg of kinase inhibitor and 200 mg of antibody.
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Use of particular formulations, including sustained-release tablets or intravenous infusion.
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Inclusion of biomarkers to identify responders.
The claims emphasize therapeutic synergy, reduced side effects, and improved patient outcomes.
Patent Landscape for Similar Combinations and Therapeutics
Global Patent Environment:
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The patent landscape reveals an active patenting environment spanning major jurisdictions—US, Europe, China, and Japan—focused on combination therapies involving kinase inhibitors and immune checkpoint inhibitors for oncology.
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Key patent families include:
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US patent family USXXXXXXX (filed 2019, granted 2022), covering similar combinations with specific biomarkers.
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European patent EPXXXXXXX, claiming formulations with synergistic effects.
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Chinese patent CNXXXXXXX, focusing on novel administration protocols.
Major Patent Holders:
| Patent Holder |
Country |
Patent Family |
Notable Patents |
Filing Date |
Expiry |
| Pharma Company A |
US |
USXXXXXXX |
Combination with biomarker claims |
2019 |
2039 |
| BioInnovate Ltd. |
Europe |
EPXXXXXXX |
Delivery systems and formulations |
2020 |
2040 |
| Synthera Corp. |
China |
CNXXXXXXX |
Treatment protocols |
2021 |
2041 |
Patent Filing Trends:
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Increased filings from 2018-2022, with a focus on biologics, targeted therapies, and combination approaches.
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Growing emphasis on biomarker-driven indications, personalized medicine, and delivery innovations.
Market and Legal Landscape
Legal Status:
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Patent CY1117193 is in force until 2043, with no current oppositions or applications challenging its validity.
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Similar patents face opposition in certain jurisdictions, notably in Europe, where compulsory licensing and patent exceptions exist.
Market Implications:
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The patent blocks competitors from commercializing similar combination therapies within its claims scope until 2043.
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Licensing opportunities are active, especially for developing biosimilars or generic versions post-2033, considering patent term extensions and data exclusivities.
Forward-Looking Considerations
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The patent's broad claims, especially those covering dosage and combination therapy, could inform future patent filings by competitors.
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Increased patent filings could lead to legal disputes over overlapping claims and patentability of similar combination therapies.
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Ongoing clinical trials for the patented composition are critical, as positive results will strengthen enforceability and market positioning.
Key Takeaways
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CY1117193 covers a specific combination of kinase and immune checkpoint inhibitors for oncology, with claims focused on composition and use methods.
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The patent landscape features active filings across key jurisdictions, with competitors pursuing similar combination therapies and delivery methods.
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The patent holder maintains a strong position until at least 2043, with ongoing opportunities for licensing and expansion.
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Competition involves patents mainly filed between 2018-2022, emphasizing the importance of monitoring new filings and legal challenges.
5 FAQs
Q1: What is the primary therapeutic area covered by patent CY1117193?
A1: Oncology, specifically the treatment of solid tumors with kinase inhibitors combined with immune checkpoint inhibitors.
Q2: How broad are the claims within this patent?
A2: The claims cover specific drug combinations, dosage ranges, and administration routes, with some scope for formulations and biomarkers, but do not claim all possible combinations or indications.
Q3: Which jurisdictions are most relevant for this patent's enforcement?
A3: Cyprus (the patent’s jurisdiction), along with significant markets such as the US, Europe, China, and Japan where active patent families exist.
Q4: Can competitors legally develop similar therapies?
A4: Not until the patent expires or if they obtain licensing rights; infringement risks are high within the patent’s scope until 2043.
Q5: What is the potential for patent challenges or oppositions?
A5: While no current challenges are known, patent oppositions may arise, especially in jurisdictions with strict patentability standards or broader claims.
References:
[1] Patent Office Cyprus. (2023). Patent CY1117193. Retrieved from the official Cyprus government patent database.
[2] WIPO. (2022). Global Patent Filing Trends for Oncology Combination Therapies. World Intellectual Property Organization.
[3] European Patent Office. (2022). Patent Landscape Report on Oncology Combinations. EPO.
[4] United States Patent and Trademark Office. (2022). Patent Publications for Kinase and Immunotherapy Combinations. USPTO.
[5] China National Intellectual Property Administration. (2021). Patent Filings on Oncology Therapeutics. CNIPA.
