List of Excipients in Branded Drug ALL DAY ALLERGY RELIEF

Company	Tradename	Ingredient	NDC	Excipient	Potential Generic Entry
P & L Development LLC	ALL DAY ALLERGY RELIEF	cetirizine hcl	59726-212	FD&C YELLOW NO. 6
P & L Development LLC	ALL DAY ALLERGY RELIEF	cetirizine hcl	59726-212	GELATIN
P & L Development LLC	ALL DAY ALLERGY RELIEF	cetirizine hcl	59726-212	GLYCERIN

Generic Drugs Containing ALL DAY ALLERGY RELIEF

Company	Ingredient	NDC	Excipient
Safeway Inc	loratadine	21130-914	CELLULOSE, MICROCRYSTALLINE
Safeway Inc	loratadine	21130-914	LACTOSE MONOHYDRATE
Safeway Inc	loratadine	21130-914	MAGNESIUM STEARATE

What are the Most Frequently-Used Excipients in ALL DAY ALLERGY RELIEF?

# Of NDCs	Excipient
6	BUTYLATED HYDROXYTOLUENE
17	CELLULOSE, MICROCRYSTALLINE
3	CROSCARMELLOSE SODIUM

Excipient Strategy and Commercial Opportunities for ALL DAY ALLERGY RELIEF

Last updated: February 26, 2026

What are the key excipient considerations for ALL DAY ALLERGY RELIEF?

Excipient selection significantly impacts drug stability, bioavailability, manufacturability, and patient compliance. For an allergy relief formulation designed for sustained, 24-hour action, the choice of excipients must support controlled release, minimize adverse reactions, and optimize shelf stability.

Core excipient roles:

• Release modulators: To control drug release rate, prevent burst release, and sustain effect over 24 hours.
• Binders and fillers: To ensure tablet integrity and uniformity.
• Lubricants and disintegrants: To facilitate manufacturing processes and appropriate disintegration timing.
• Stabilizers: To prevent moisture ingress and chemical degradation.

Typical excipients used:

Function	Common excipients	Product considerations
Controlled release	Polyethylene oxide, hydroxypropyl methylcellulose (HPMC)	Promote sustained release; minimize burst effect
Binders	Microcrystalline cellulose, povidone	Ensure tablet cohesion
Disintegrants	Croscarmellose sodium, sodium starch glycolate	Enable efficient disintegration during absorption
Lubricants	Magnesium stearate, talc	Reduce friction during manufacturing
Stabilizers	Antioxidants (e.g., ascorbic acid)	Enhance chemical stability

How do excipient strategies optimize commercial prospects?

Enhancing formulation stability and shelf life

Use of antioxidant stabilizers and moisture barriers prevents degradation, extending product shelf life, reducing returns, and improving consumer confidence.

Supporting controlled-release mechanisms

Strategic incorporation of specific polymers allows the drug to deliver over 12–24 hours, reducing dosing frequency. This feature aligns with consumer demand for convenience, supports premium pricing, and differentiates products in a competitive market.

Streamlining manufacturing processes

Choosing excipients with well-characterized behavior reduces production costs and variability. High-quality excipients enable high-speed, scalable production lines, improving margins.

Regulatory compliance and consumer safety

Use of excipients with established safety profiles supports faster approval and minimizes regulatory hurdles. Recognizable excipients foster consumer trust, especially in OTC allergy formulations.

Market differentiation opportunities

Developing formulations with novel excipients—such as multifunctional hydrogels or bioadhesives—can lead to proprietary delivery platforms. Such innovation offers opportunities for patenting and exclusivity.

What are the unmet market needs and how do excipient choices address them?

Addressing rapid onset and sustained relief

Combining fast-disintegrating excipients for quick initial action with controlled-release components for prolonged effect satisfies unmet consumer preferences.

Minimizing side effects

Selecting excipients with low allergenic potential or tolerability issues enhances patient safety, reduces adverse events, and broadens target demographics.

Improving portability and compliance

Developing solid dosage forms with excipient matrices that support miniaturization and portability improves adherence, especially among elderly or pediatric populations.

What are the key regulatory considerations?

• Use of excipients recognized in pharmacopeias (e.g., USP, EP).
• Documentation of safety profiles and manufacturing processes.
• Compatibility with active pharmaceutical ingredient (API).
• Labeling transparency regarding excipient content.

Market overview and opportunities

• The global allergy medications market was valued at USD 29.61 billion in 2021 and is projected to grow at 5.2% CAGR through 2028[1].
• Among OTC drugs, multi-dose, long-acting formulations are gaining popularity.
• Innovation in excipient technology supports differentiation in sustained-release allergy relief products.
• Patent protection on proprietary excipient combinations or delivery systems offers competitive advantages.

Key Takeaways

• Excipient strategies for ALL DAY ALLERGY RELIEF focus on controlled release, stability, manufacturability, and safety.
• Using proven excipients reduces regulatory risk and supports commercial scalability.
• Formulations with innovative excipient matrices can achieve competitive differentiation.
• Market growth driven by consumer preferences for convenience and extended relief provides opportunities for premium products.

FAQs

Q1: What excipients are most suitable for controlled-release allergy relief tablets?
Polyethylene oxide and HPMC are common for their film-forming, gel-forming, and sustained-release properties.

Q2: How can excipient choice improve patient compliance?
By enabling once-daily dosing, reducing side effects through tolerable excipients, and creating easy-to-swallow formulations.

Q3: What regulatory challenges exist with excipients in allergy medications?
Ensuring excipients are recognized as safe, properly documented, and compatible with the API. Novel excipients require additional safety data.

Q4: How does excipient selection influence manufacturing costs?
High-quality, readily available excipients streamline processes, reduce batch failures, and lower overall production expenses.

Q5: Are there patent opportunities related to excipients in allergy relief?
Yes, proprietary combinations and innovative matrices can be protected, providing a competitive edge.

---

[1] Grand View Research. (2022). Allergy medications market size, share & trends analysis.