Investigational Drug Information for Vactosertib
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What is the drug development status for Vactosertib?
Vactosertib is an investigational drug.
There have been 18 clinical trials for Vactosertib.
The most recent clinical trial was a Phase 1 trial, which was initiated on July 12th 2019.
The most common disease conditions in clinical trials are Colorectal Neoplasms, Adenocarcinoma, and Neoplasms. The leading clinical trial sponsors are MedPacto, Inc., Samsung Medical Center, and Merck Sharp & Dohme Corp.
There are two US patents protecting this investigational drug and thirty-four international patents.
Summary for Vactosertib
| US Patents | 2 |
| International Patents | 34 |
| US Patent Applications | 59 |
| WIPO Patent Applications | 45 |
| Japanese Patent Applications | 2 |
| Clinical Trial Progress | Phase 1 (2019-07-12) |
| Vendors | 69 |
Recent Clinical Trials for Vactosertib
| Title | Sponsor | Phase |
|---|---|---|
| Assessing Clinical Trial Outcome of Patients With Relapsed/Refractor Metastatic Osteosarcoma in Adolescents and Adults | MedPacto, Inc. | Phase 1/Phase 2 |
| Antitumor Activity of Vactosertib in Combination With Pembrolizumab in Acral and Mucosal Melanoma Patients Progressed From Prior Immune Check Point Inhibitor | Yonsei University | Phase 2 |
| Natural Killer (NK) Cells in Combination With Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in Cancer | Jennifer Eva Selfridge | Phase 1 |
Clinical Trial Summary for Vactosertib
Top disease conditions for Vactosertib
Top clinical trial sponsors for Vactosertib
US Patents for Vactosertib
| Drugname | Patent Number | Patent Title | Patent Assignee | Estimated Expiration |
|---|---|---|---|---|
| Vactosertib | ⤷ Try a Trial | 1,5-dihydro-2H-pyrrol-2-one compounds and methods of using same | Frequency Therapeutics, Inc. (Woburn, MA) | ⤷ Try a Trial |
| Vactosertib | ⤷ Try a Trial | Methods and compositions relating to hematopoietic stem cell expansion, enrichment, and maintenance | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, MA) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, MA) | ⤷ Try a Trial |
| >Drugname | >Patent Number | >Patent Title | >Patent Assignee | >Estimated Expiration |
International Patents for Vactosertib
| Drugname | Country | Document Number | Estimated Expiration | Related US Patent |
|---|---|---|---|---|
| Vactosertib | European Patent Office | EP3313420 | 2035-06-25 | ⤷ Try a Trial |
| Vactosertib | Japan | JP2018519298 | 2035-06-25 | ⤷ Try a Trial |
| Vactosertib | Japan | JP2022028821 | 2035-06-25 | ⤷ Try a Trial |
| >Drugname | >Country | >Document Number | >Estimated Expiration | >Related US Patent |
