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Last Updated: October 5, 2024

Investigational Drug Information for Vactosertib


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What is the drug development status for Vactosertib?

Vactosertib is an investigational drug.

There have been 18 clinical trials for Vactosertib. The most recent clinical trial was a Phase 1 trial, which was initiated on November 22nd 2019.

The most common disease conditions in clinical trials are Colorectal Neoplasms, Adenocarcinoma, and Neoplasms. The leading clinical trial sponsors are MedPacto, Inc., Yonsei University, and Samsung Medical Center.

There are two US patents protecting this investigational drug and thirty-four international patents.

Recent Clinical Trials for Vactosertib
TitleSponsorPhase
Assessing Clinical Trial Outcome of Patients With Relapsed/Refractor Metastatic Osteosarcoma in Adolescents and AdultsMedPacto, Inc.Phase 1/Phase 2
Antitumor Activity of Vactosertib in Combination With Pembrolizumab in Acral and Mucosal Melanoma Patients Progressed From Prior Immune Check Point InhibitorYonsei UniversityPhase 2
Natural Killer (NK) Cells in Combination With Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in CancerJennifer Eva SelfridgePhase 1

See all Vactosertib clinical trials

Clinical Trial Summary for Vactosertib

Top disease conditions for Vactosertib
Top clinical trial sponsors for Vactosertib

See all Vactosertib clinical trials

US Patents for Vactosertib

Drugname Patent Number Patent Title Patent Assignee Estimated Expiration
Vactosertib ⤷  Sign Up 1,5-dihydro-2H-pyrrol-2-one compounds and methods of using same Frequency Therapeutics, Inc. (Woburn, MA) ⤷  Sign Up
Vactosertib ⤷  Sign Up Methods and compositions relating to hematopoietic stem cell expansion, enrichment, and maintenance CHILDREN'S MEDICAL CENTER CORPORATION (Boston, MA) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, MA) ⤷  Sign Up
>Drugname >Patent Number >Patent Title >Patent Assignee >Estimated Expiration

International Patents for Vactosertib

Drugname Country Document Number Estimated Expiration Related US Patent
Vactosertib European Patent Office EP3313420 2035-06-25 ⤷  Sign Up
Vactosertib Japan JP2018519298 2035-06-25 ⤷  Sign Up
Vactosertib Japan JP2022028821 2035-06-25 ⤷  Sign Up
Vactosertib Japan JP6980534 2035-06-25 ⤷  Sign Up
>Drugname >Country >Document Number >Estimated Expiration >Related US Patent

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